TY - JOUR
T1 - Frequency and large T (LT) sequence of JC polyomavirus DNA in oligodendrocytes, astrocytes and granular cells in Non-PML brain
AU - Bayliss, Julianne
AU - Jankovic-Karasoulos, Tanja
AU - McLean, Catriona Ann
PY - 2012
Y1 - 2012
N2 - Pure populations of astrocytes,
oligodendrocytes, CGNs and microglia from frontal cortex and cerebellum of 17 non-PML
patients (9 immunocompetent; 8 immunosuppressed) were isolated by laser capture microdissection
(LCM). JCV large T (LT) antigen DNA was detected by triple nested polymerase
chain reaction (PCR). Sequence analysis was performed to assess LT gene variation. JCV
DNA was detected in oligodendrocytes, astrocytes and CGNs of non-PML brains.
AB - Pure populations of astrocytes,
oligodendrocytes, CGNs and microglia from frontal cortex and cerebellum of 17 non-PML
patients (9 immunocompetent; 8 immunosuppressed) were isolated by laser capture microdissection
(LCM). JCV large T (LT) antigen DNA was detected by triple nested polymerase
chain reaction (PCR). Sequence analysis was performed to assess LT gene variation. JCV
DNA was detected in oligodendrocytes, astrocytes and CGNs of non-PML brains.
UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1750-3639.2011.00538.x/pdf
U2 - 10.1111/j.1750-3639.2011.00538.x.
DO - 10.1111/j.1750-3639.2011.00538.x.
M3 - Article
SN - 1015-6305
VL - 22
SP - 329
EP - 336
JO - Brain Pathology
JF - Brain Pathology
IS - 3
ER -