Frequency and characteristics of hospital admissions associated with drug-related problems in paediatrics

Kylie L. Easton, Colin B. Chapman, Jo Anne E. Brien

Research output: Contribution to journalReview ArticleResearchpeer-review

50 Citations (Scopus)


Aim: To determine the frequency of paediatric hospital admissions associated with drug-related problems (DRPs) at two Australian hospitals. Methods: The investigator and ward pharmacists prospectively screened eligible patients. A multidisciplinary panel reviewed data and established causality, preventability and clinical significance classifications. Results: Over 22 weeks of data collection, a total of 11 564 patients were admitted, 2933 met eligibility criteria. Of those eligible, 127 [4.3%, 95% confidence interval (CI) 3.6, 5.0] were judged to have hospital admissions associated with DRPs. Direct costs associated with DRPs identified totalled £100 707. Of the 81 cases assessed for preventability, 46.9% were deemed preventable. Conclusions: This research has provided information on the nature and characteristics of paediatric DRPs associated with hospital admissions.

Original languageEnglish
Pages (from-to)611-615
Number of pages5
JournalBritish Journal of Clinical Pharmacology
Issue number5
Publication statusPublished - 1 May 2004


  • Drug-related problems
  • Hospital admissions
  • Non-adherence
  • Paediatrics

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