Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina: Intrinsic signal imaging and linear model analysis.

Shaun L. Cloherty; Markus A Hietanen; Gregg J. Suaning; Michael Robert Ibbotson

Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina: Intrinsic signal imaging and linear model analysis.

Shaun L. Cloherty, Markus A Hietanen, Gregg J. Suaning, Michael Robert Ibbotson

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

We performed optical intrinsic signal imaging of cat primary visual cortex (Area 17 and 18) while delivering bipolar electrical stimulation to the retina by way of a supra-choroidal electrode array. Using a general linear model (GLM) analysis we identified statistically significant (p < 0.01) activation in a localized region of cortex following supra-threshold electrical stimulation at a single retinal locus. (1) demonstrate that intrinsic signal imaging combined with linear model analysis provides a powerful tool for assessing cortical responses to prosthetic stimulation, and (2) confirm that supra-choroidal electrical stimulation can achieve localized activation of the cortex consistent with focal activation of the retina.

Original language	English
Title of host publication	Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2010
Pages	6765-6768
Number of pages	4
Publication status	Published - 2010
Externally published	Yes
Event	International Conference of the IEEE Engineering in Medicine and Biology Society 2010 - Sheraton Buenos Aires Hotel, Buenos Aires, Argentina Duration: 31 Aug 2010 → 4 Sep 2010 Conference number: 32nd https://ieeexplore.ieee.org/xpl/conhome/5608545/proceeding (Proceedings)

Conference

Conference	International Conference of the IEEE Engineering in Medicine and Biology Society 2010
Abbreviated title	EMBC 2010
Country/Territory	Argentina
City	Buenos Aires
Period	31/08/10 → 4/09/10
Internet address	https://ieeexplore.ieee.org/xpl/conhome/5608545/proceeding (Proceedings)

Cite this

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title = "Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina: Intrinsic signal imaging and linear model analysis.",

abstract = "We performed optical intrinsic signal imaging of cat primary visual cortex (Area 17 and 18) while delivering bipolar electrical stimulation to the retina by way of a supra-choroidal electrode array. Using a general linear model (GLM) analysis we identified statistically significant (p < 0.01) activation in a localized region of cortex following supra-threshold electrical stimulation at a single retinal locus. (1) demonstrate that intrinsic signal imaging combined with linear model analysis provides a powerful tool for assessing cortical responses to prosthetic stimulation, and (2) confirm that supra-choroidal electrical stimulation can achieve localized activation of the cortex consistent with focal activation of the retina.",

author = "Cloherty, {Shaun L.} and Hietanen, {Markus A} and Suaning, {Gregg J.} and Ibbotson, {Michael Robert}",

year = "2010",

language = "English",

pages = "6765--6768",

booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2010",

note = "International Conference of the IEEE Engineering in Medicine and Biology Society 2010, EMBC 2010 ; Conference date: 31-08-2010 Through 04-09-2010",

url = "https://ieeexplore.ieee.org/xpl/conhome/5608545/proceeding",

}

Cloherty, SL, Hietanen, MA, Suaning, GJ & Ibbotson, MR 2010, Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina: Intrinsic signal imaging and linear model analysis. in Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2010. pp. 6765-6768, International Conference of the IEEE Engineering in Medicine and Biology Society 2010, Buenos Aires, Argentina, 31/08/10.

Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina : Intrinsic signal imaging and linear model analysis. / Cloherty, Shaun L.; Hietanen, Markus A; Suaning, Gregg J. et al.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2010. 2010. p. 6765-6768.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

T1 - Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina

T2 - International Conference of the IEEE Engineering in Medicine and Biology Society 2010

AU - Cloherty, Shaun L.

AU - Hietanen, Markus A

AU - Suaning, Gregg J.

AU - Ibbotson, Michael Robert

N1 - Conference code: 32nd

PY - 2010

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N2 - We performed optical intrinsic signal imaging of cat primary visual cortex (Area 17 and 18) while delivering bipolar electrical stimulation to the retina by way of a supra-choroidal electrode array. Using a general linear model (GLM) analysis we identified statistically significant (p < 0.01) activation in a localized region of cortex following supra-threshold electrical stimulation at a single retinal locus. (1) demonstrate that intrinsic signal imaging combined with linear model analysis provides a powerful tool for assessing cortical responses to prosthetic stimulation, and (2) confirm that supra-choroidal electrical stimulation can achieve localized activation of the cortex consistent with focal activation of the retina.

AB - We performed optical intrinsic signal imaging of cat primary visual cortex (Area 17 and 18) while delivering bipolar electrical stimulation to the retina by way of a supra-choroidal electrode array. Using a general linear model (GLM) analysis we identified statistically significant (p < 0.01) activation in a localized region of cortex following supra-threshold electrical stimulation at a single retinal locus. (1) demonstrate that intrinsic signal imaging combined with linear model analysis provides a powerful tool for assessing cortical responses to prosthetic stimulation, and (2) confirm that supra-choroidal electrical stimulation can achieve localized activation of the cortex consistent with focal activation of the retina.

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M3 - Conference Paper

C2 - 21095835

SP - 6765

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BT - Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) 2010

Y2 - 31 August 2010 through 4 September 2010

ER -

Focal activation of primary visual cortex following supra-choroidal electrical stimulation of the retina: Intrinsic signal imaging and linear model analysis.

Abstract

Conference

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