Fluorescent Sensors for Biological Metal Ions

A. Kaur, Z. Lim, K. Yang, E. J. New

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

5 Citations (Scopus)

Abstract

Metal ions play key roles in biological processes, but much remains to be understood about the roles of metal ions in health and disease. Fluorescent metal sensors provide the ability to selectively image the bioavailable pool of a metal ion. This article details the design considerations in preparing fluorescent metal sensors, including the metal selectivity, fluorescence response, and biological compatibility.

Original languageEnglish
Title of host publicationComprehensive Supramolecular Chemistry II
Subtitle of host publicationFluorescent Sensors and Imaging Agents
EditorsTimothy E. Glass
Place of PublicationNetherlands
PublisherElsevier
Chapter8.14
Pages295-317
Number of pages23
Volume8
ISBN (Electronic)9780128031988
ISBN (Print)9780128031995
DOIs
Publication statusPublished - 22 Jun 2017
Externally publishedYes

Keywords

  • Bioimaging
  • Chemosensor
  • Fluorescence
  • Fluorophore
  • Intracellular
  • Ligand
  • Metal ions
  • Metallobiology
  • Molecular recognition
  • Probe
  • Selectivity

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