Original language | English |
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Title of host publication | Comprehensive Supramolecular Chemistry II |
Subtitle of host publication | Fluorescent Sensors and Imaging Agents |
Editors | Timothy E. Glass |
Place of Publication | Netherlands |
Publisher | Elsevier |
Chapter | 8.14 |
Pages | 295-317 |
Number of pages | 23 |
Volume | 8 |
ISBN (Electronic) | 9780128031988 |
ISBN (Print) | 9780128031995 |
DOIs | |
Publication status | Published - 22 Jun 2017 |
Externally published | Yes |
Abstract
Metal ions play key roles in biological processes, but much remains to be understood about the roles of metal ions in health and disease. Fluorescent metal sensors provide the ability to selectively image the bioavailable pool of a metal ion. This article details the design considerations in preparing fluorescent metal sensors, including the metal selectivity, fluorescence response, and biological compatibility.
Keywords
- Bioimaging
- Chemosensor
- Fluorescence
- Fluorophore
- Intracellular
- Ligand
- Metal ions
- Metallobiology
- Molecular recognition
- Probe
- Selectivity