The development of advanced and flexible manufacturing systems and workholding systems that easily adjust in high-volume or low volume production environments was discussed. The flexible manufacturing systems were defined as a production unit capable of manufacturing a family of products with a minimum amount of manual intervention. Such a system consisted of workstations equipped with multi-axis robotic systems to perform manufacturing operations. The approach to workholding involved designing and manufacturing dedicated fixtures that were single-purpose devices designed for specific parts and manufacturing operations. The future research would focus on the development of systems capable of manufacturing a wider family of workpieces and reducing cost.