Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98

Alan S Coates; Aparna Keshaviah; Beat Thurlimann; Henning Mouridsen; Louis Mauriac; John F Forbes; Robert Paridaens; Monica Castiglione-Gertsch; Richard D Gelber; Marco Colleoni; Istvan Lang; Lucia Del Mastro; Ian Smith; Jacquie Chirgwin; Jean-Marie Nogaret; Tadeusz Pienkowski; Andrew Wardley; Erik H Jakobsen; Karen N Price; Aron Goldhirsch

Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98

Alan S Coates, Aparna Keshaviah, Beat Thurlimann, Henning Mouridsen, Louis Mauriac, John F Forbes, Robert Paridaens, Monica Castiglione-Gertsch, Richard D Gelber, Marco Colleoni, Istvan Lang, Lucia Del Mastro, Ian Smith, Jacquie Chirgwin, Jean-Marie Nogaret, Tadeusz Pienkowski, Andrew Wardley, Erik H Jakobsen, Karen N Price, Aron Goldhirsch

Eastern Clinical Research Unit

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Previous analyses of the Breast International Group (BIG) 1-98 four-arm study compared initial therapy with letrozole or tamoxifen including patients randomly assigned to sequential treatment whose information was censored at the time of therapy change. Because this presentation may unduly reflect early events, the present analysis is limited to patients randomly assigned to the continuous therapy arms and includes protocol-defined updated results

Original language	English
Pages (from-to)	486 - 492
Number of pages	7
Journal	Journal of Clinical Oncology
Volume	25
Issue number	5
Publication status	Published - 2007

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Coates, A. S., Keshaviah, A., Thurlimann, B., Mouridsen, H., Mauriac, L., Forbes, J. F., Paridaens, R., Castiglione-Gertsch, M., Gelber, R. D., Colleoni, M., Lang, I., Mastro, L. D., Smith, I., Chirgwin, J., Nogaret, J-M., Pienkowski, T., Wardley, A., Jakobsen, E. H., Price, K. N., & Goldhirsch, A. (2007). Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98. Journal of Clinical Oncology, 25(5), 486 - 492.

Coates, Alan S ; Keshaviah, Aparna ; Thurlimann, Beat ; Mouridsen, Henning ; Mauriac, Louis ; Forbes, John F ; Paridaens, Robert ; Castiglione-Gertsch, Monica ; Gelber, Richard D ; Colleoni, Marco ; Lang, Istvan ; Mastro, Lucia Del ; Smith, Ian ; Chirgwin, Jacquie ; Nogaret, Jean-Marie ; Pienkowski, Tadeusz ; Wardley, Andrew ; Jakobsen, Erik H ; Price, Karen N ; Goldhirsch, Aron. / Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98. In: Journal of Clinical Oncology. 2007 ; Vol. 25, No. 5. pp. 486 - 492.

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title = "Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98",

abstract = "Previous analyses of the Breast International Group (BIG) 1-98 four-arm study compared initial therapy with letrozole or tamoxifen including patients randomly assigned to sequential treatment whose information was censored at the time of therapy change. Because this presentation may unduly reflect early events, the present analysis is limited to patients randomly assigned to the continuous therapy arms and includes protocol-defined updated results",

author = "Coates, {Alan S} and Aparna Keshaviah and Beat Thurlimann and Henning Mouridsen and Louis Mauriac and Forbes, {John F} and Robert Paridaens and Monica Castiglione-Gertsch and Gelber, {Richard D} and Marco Colleoni and Istvan Lang and Mastro, {Lucia Del} and Ian Smith and Jacquie Chirgwin and Jean-Marie Nogaret and Tadeusz Pienkowski and Andrew Wardley and Jakobsen, {Erik H} and Price, {Karen N} and Aron Goldhirsch",

year = "2007",

language = "English",

volume = "25",

pages = "486 -- 492",

journal = "Journal of Clinical Oncology",

issn = "0732-183X",

publisher = "American Society of Clinical Oncology",

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Coates, AS, Keshaviah, A, Thurlimann, B, Mouridsen, H, Mauriac, L, Forbes, JF, Paridaens, R, Castiglione-Gertsch, M, Gelber, RD, Colleoni, M, Lang, I, Mastro, LD, Smith, I, Chirgwin, J, Nogaret, J-M, Pienkowski, T, Wardley, A, Jakobsen, EH, Price, KN & Goldhirsch, A 2007, 'Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98', Journal of Clinical Oncology, vol. 25, no. 5, pp. 486 - 492.

Five years of letrozole compared with tamoxifen as initial adjuvant thrapy for postmenopausal women with endocrine-responsive early breast cancer update of study BIG 1-98. / Coates, Alan S; Keshaviah, Aparna; Thurlimann, Beat; Mouridsen, Henning; Mauriac, Louis; Forbes, John F; Paridaens, Robert; Castiglione-Gertsch, Monica; Gelber, Richard D; Colleoni, Marco; Lang, Istvan; Mastro, Lucia Del; Smith, Ian; Chirgwin, Jacquie; Nogaret, Jean-Marie; Pienkowski, Tadeusz; Wardley, Andrew; Jakobsen, Erik H; Price, Karen N; Goldhirsch, Aron.

In: Journal of Clinical Oncology, Vol. 25, No. 5, 2007, p. 486 - 492.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Mouridsen, Henning

AU - Mauriac, Louis

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AU - Lang, Istvan

AU - Mastro, Lucia Del

AU - Smith, Ian

AU - Chirgwin, Jacquie

AU - Nogaret, Jean-Marie

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AU - Goldhirsch, Aron

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AB - Previous analyses of the Breast International Group (BIG) 1-98 four-arm study compared initial therapy with letrozole or tamoxifen including patients randomly assigned to sequential treatment whose information was censored at the time of therapy change. Because this presentation may unduly reflect early events, the present analysis is limited to patients randomly assigned to the continuous therapy arms and includes protocol-defined updated results

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