Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Andrew Pipingas, Andrew J Sinclair, Kevin David Croft, Andrzej S Januszewski, Alicia J Jenkins, Trevor A Mori, Robyn Cockerell, Natalie Grima, Con Stough, Andrew B Scholey, Stephen Myers, Avni Sali, Matthew P Pase

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol
Original languageEnglish
Pages (from-to)949 - 957
Number of pages9
JournalJournal of Functional Foods
Volume19
DOIs
Publication statusPublished - 2015

Cite this

Pipingas, Andrew ; Sinclair, Andrew J ; Croft, Kevin David ; Januszewski, Andrzej S ; Jenkins, Alicia J ; Mori, Trevor A ; Cockerell, Robyn ; Grima, Natalie ; Stough, Con ; Scholey, Andrew B ; Myers, Stephen ; Sali, Avni ; Pase, Matthew P. / Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial. In: Journal of Functional Foods. 2015 ; Vol. 19. pp. 949 - 957.
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abstract = "The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol",
author = "Andrew Pipingas and Sinclair, {Andrew J} and Croft, {Kevin David} and Januszewski, {Andrzej S} and Jenkins, {Alicia J} and Mori, {Trevor A} and Robyn Cockerell and Natalie Grima and Con Stough and Scholey, {Andrew B} and Stephen Myers and Avni Sali and Pase, {Matthew P}",
year = "2015",
doi = "10.1016/j.jff.2014.10.028",
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volume = "19",
pages = "949 -- 957",
journal = "Journal of Functional Foods",
issn = "1756-4646",
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Pipingas, A, Sinclair, AJ, Croft, KD, Januszewski, AS, Jenkins, AJ, Mori, TA, Cockerell, R, Grima, N, Stough, C, Scholey, AB, Myers, S, Sali, A & Pase, MP 2015, 'Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial' Journal of Functional Foods, vol. 19, pp. 949 - 957. https://doi.org/10.1016/j.jff.2014.10.028

Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial. / Pipingas, Andrew; Sinclair, Andrew J; Croft, Kevin David; Januszewski, Andrzej S; Jenkins, Alicia J; Mori, Trevor A; Cockerell, Robyn; Grima, Natalie; Stough, Con; Scholey, Andrew B; Myers, Stephen; Sali, Avni; Pase, Matthew P.

In: Journal of Functional Foods, Vol. 19, 2015, p. 949 - 957.

Research output: Contribution to journalArticleResearchpeer-review

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T1 - Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

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AU - Sinclair, Andrew J

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AU - Januszewski, Andrzej S

AU - Jenkins, Alicia J

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AU - Cockerell, Robyn

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AU - Stough, Con

AU - Scholey, Andrew B

AU - Myers, Stephen

AU - Sali, Avni

AU - Pase, Matthew P

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