Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Andrew Pipingas, Andrew J Sinclair, Kevin David Croft, Andrzej S Januszewski, Alicia J Jenkins, Trevor A Mori, Robyn Cockerell, Natalie Grima, Con Stough, Andrew B Scholey, Stephen Myers, Avni Sali, Matthew P Pase

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13 Citations (Scopus)


The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol
Original languageEnglish
Pages (from-to)949 - 957
Number of pages9
JournalJournal of Functional Foods
Publication statusPublished - 2015

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