Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Andrew Pipingas; Andrew J Sinclair; Kevin David Croft; Andrzej S Januszewski; Alicia J Jenkins; Trevor A Mori; Robyn Cockerell; Natalie Grima; Con Stough; Andrew B Scholey; Stephen Myers; Avni Sali; Matthew P Pase

doi:10.1016/j.jff.2014.10.028

Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Andrew Pipingas, Andrew J Sinclair, Kevin David Croft, Andrzej S Januszewski, Alicia J Jenkins, Trevor A Mori, Robyn Cockerell, Natalie Grima, Con Stough, Andrew B Scholey, Stephen Myers, Avni Sali, Matthew P Pase

Psychology

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Abstract

The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol

Original language	English
Pages (from-to)	949 - 957
Number of pages	9
Journal	Journal of Functional Foods
Volume	19
DOIs	https://doi.org/10.1016/j.jff.2014.10.028
Publication status	Published - 2015

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10.1016/j.jff.2014.10.028

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Pipingas, A., Sinclair, A. J., Croft, K. D., Januszewski, A. S., Jenkins, A. J., Mori, T. A., Cockerell, R., Grima, N., Stough, C., Scholey, A. B., Myers, S., Sali, A., & Pase, M. P. (2015). Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial. Journal of Functional Foods, 19, 949 - 957. https://doi.org/10.1016/j.jff.2014.10.028

@article{eb759d0f0caa4534829cb2454f327afb,

title = "Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial",

abstract = "The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol",

author = "Andrew Pipingas and Sinclair, {Andrew J} and Croft, {Kevin David} and Januszewski, {Andrzej S} and Jenkins, {Alicia J} and Mori, {Trevor A} and Robyn Cockerell and Natalie Grima and Con Stough and Scholey, {Andrew B} and Stephen Myers and Avni Sali and Pase, {Matthew P}",

year = "2015",

doi = "10.1016/j.jff.2014.10.028",

language = "English",

volume = "19",

pages = "949 -- 957",

journal = "Journal of Functional Foods",

issn = "1756-4646",

publisher = "Elsevier",

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Pipingas, A, Sinclair, AJ, Croft, KD, Januszewski, AS, Jenkins, AJ, Mori, TA, Cockerell, R, Grima, N, Stough, C, Scholey, AB, Myers, S, Sali, A & Pase, MP 2015, 'Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial', Journal of Functional Foods, vol. 19, pp. 949 - 957. https://doi.org/10.1016/j.jff.2014.10.028

TY - JOUR

T1 - Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

AU - Pipingas, Andrew

AU - Sinclair, Andrew J

AU - Croft, Kevin David

AU - Januszewski, Andrzej S

AU - Jenkins, Alicia J

AU - Mori, Trevor A

AU - Cockerell, Robyn

AU - Grima, Natalie

AU - Stough, Con

AU - Scholey, Andrew B

AU - Myers, Stephen

AU - Sali, Avni

AU - Pase, Matthew P

PY - 2015

Y1 - 2015

N2 - The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol

AB - The effects of daily fish oil supplementation, with and without multivitamins, on biochemical markers of health were examined. Healthy adults (N = 160) were randomised to receive 3 g of salmon oil with a multivitamin, 6 g of salmon oil with a multivitamin, 6 g of salmon oil in isolation or placebo in a double-blind fashion on a daily basis for 16 weeks. Relative to placebo, both 6 g salmon oil groups displayed significantly lower F2-isoprostane levels at endpoint. Increases in red blood cell polyunsaturated fatty acids correlated with reductions in F2-isoprostanes. Treatment had no effect on inflammatory cytokines, C-reactive protein, fibrinogen, cholesterol or triacylglycerol

UR - http://goo.gl/Ib9DRJ

U2 - 10.1016/j.jff.2014.10.028

DO - 10.1016/j.jff.2014.10.028

M3 - Article

VL - 19

SP - 949

EP - 957

JO - Journal of Functional Foods

JF - Journal of Functional Foods

SN - 1756-4646

ER -

Fish oil and multivitamin supplementation reduces oxidative stress but not inflammation in healthy older adults: a randomised controlled trial

Abstract

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