Abstract
The idea that foods consumed for pure pleasure could provide health benefits received much recognition in the recent years. Among these foods, cocoa and dark chocolate are particularly rich in procyanidins, one of the major dietary families of polyphenols. We developed the first asymmetric total synthesis of procyanidin B2 and applied it to the preparation of a regioselectively radiolabeled 14C-analogue, which will be used to strengthen our knowledge on the metabolism of procyanidins.
Original language | English |
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Pages (from-to) | 6069-6078 |
Number of pages | 10 |
Journal | European Journal of Organic Chemistry |
Issue number | 36 |
DOIs | |
Publication status | Published - 1 Dec 2008 |
Externally published | Yes |
Keywords
- Natural products
- Polyphenols
- Radiochemistry
- Total synthesis