First detection of Klebsiella quasipneumoniae producing OXA-181 carbapenemase in Malaysia

Min Yi Lau, Sasheela Ponnampalavanar, Way Seah Lee, Kartini Abdul Jabar, Kek Heng Chua, Nuryana Idris, Chun Wie Chong, Polly Soo Xi Yap, Cindy Shuan Ju Teh

    Research output: Contribution to journalArticleResearchpeer-review

    Abstract

    The emergence of carbapenemase-producing Enterobacteriaceae has become a major global concern. OXA-48-like carbapenemase gene and its variants have been increasingly reported worldwide. This study reported the first OXA-181-producing Klebsiella quasipneumoniae isolate in Malaysia. This bacterium was isolated from blood specimen of a three-year-old boy with Alagille syndrome who had liver biopsy on October 2016. He had undergone liver transplant in India ten months previously. The genotypic and phenotypic characteristics of the strain were elucidated in this study. To our best knowledge, this is the first report of OXA-181-producing K. quasipneumoniae in Malaysia.

    Original languageEnglish
    Pages (from-to)1058-1061
    Number of pages4
    JournalJournal of Infection and Chemotherapy
    Volume26
    Issue number10
    DOIs
    Publication statusPublished - Oct 2020

    Keywords

    • Carbapenem resistant Enterobacteriaceae
    • Klebsiella quasipneumoniae
    • OXA-181
    • OXA-48

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