Abstract
Aims: A study was designed to assess the effects of a standardized instructional videotape on reducing interobserver variability for several commonly used observer-dependent outcome measures. Methods: During a single day, six rheumatologists independently examined six patients with fibromyalgia (FM) in a predetermined order using a Latin square design, before and after viewing a standardized videotape which demonstrated methods for performing dolorimetry and for detecting skinfold tenderness and reactive hyperaemia. Reliability coefficients were calculated based on the variance components of the analysis of variance (ANOVA) table. Results: Prestandardization reliability coefficients were <0.80 for 8 measures. Following standardization all reliability coefficients approximated to or exceeded 0.80. Conclusions: An important and beneficial effect of the standardization procedure was noted for several outcome variables. Such reductions in observer variability have the potential to diminish sample size requirements for FM antirheumatic drug studies. The use of a videotape to achieve this goal has obvious cost and convenience advantages over one-on- one training procedures.
| Original language | English |
|---|---|
| Pages (from-to) | 261-272 |
| Number of pages | 12 |
| Journal | Inflammopharmacology |
| Volume | 5 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Jan 1997 |
| Externally published | Yes |
Keywords
- Clinical trials
- Fibromyalgia
- Outcome measurement
Cite this
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Fibromyalgia antirheumatic drug trials : Effects of a standardized instructional videotape on the reliability of observer-dependent outcome measures. / Bellamy, N.; Buchbinder, R.; Hall, S.; Lowthian, P.; Patrick, M. R.; Ryan, P. F.J.; Stockman, A.; Grant, G.; Green, S.; Campbell, J.
In: Inflammopharmacology, Vol. 5, No. 3, 01.01.1997, p. 261-272.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Fibromyalgia antirheumatic drug trials
T2 - Effects of a standardized instructional videotape on the reliability of observer-dependent outcome measures
AU - Bellamy, N.
AU - Buchbinder, R.
AU - Hall, S.
AU - Lowthian, P.
AU - Patrick, M. R.
AU - Ryan, P. F.J.
AU - Stockman, A.
AU - Grant, G.
AU - Green, S.
AU - Campbell, J.
PY - 1997/1/1
Y1 - 1997/1/1
N2 - Aims: A study was designed to assess the effects of a standardized instructional videotape on reducing interobserver variability for several commonly used observer-dependent outcome measures. Methods: During a single day, six rheumatologists independently examined six patients with fibromyalgia (FM) in a predetermined order using a Latin square design, before and after viewing a standardized videotape which demonstrated methods for performing dolorimetry and for detecting skinfold tenderness and reactive hyperaemia. Reliability coefficients were calculated based on the variance components of the analysis of variance (ANOVA) table. Results: Prestandardization reliability coefficients were <0.80 for 8 measures. Following standardization all reliability coefficients approximated to or exceeded 0.80. Conclusions: An important and beneficial effect of the standardization procedure was noted for several outcome variables. Such reductions in observer variability have the potential to diminish sample size requirements for FM antirheumatic drug studies. The use of a videotape to achieve this goal has obvious cost and convenience advantages over one-on- one training procedures.
AB - Aims: A study was designed to assess the effects of a standardized instructional videotape on reducing interobserver variability for several commonly used observer-dependent outcome measures. Methods: During a single day, six rheumatologists independently examined six patients with fibromyalgia (FM) in a predetermined order using a Latin square design, before and after viewing a standardized videotape which demonstrated methods for performing dolorimetry and for detecting skinfold tenderness and reactive hyperaemia. Reliability coefficients were calculated based on the variance components of the analysis of variance (ANOVA) table. Results: Prestandardization reliability coefficients were <0.80 for 8 measures. Following standardization all reliability coefficients approximated to or exceeded 0.80. Conclusions: An important and beneficial effect of the standardization procedure was noted for several outcome variables. Such reductions in observer variability have the potential to diminish sample size requirements for FM antirheumatic drug studies. The use of a videotape to achieve this goal has obvious cost and convenience advantages over one-on- one training procedures.
KW - Clinical trials
KW - Fibromyalgia
KW - Outcome measurement
UR - http://www.scopus.com/inward/record.url?scp=0030772261&partnerID=8YFLogxK
U2 - 10.1007/s10787-997-0004-y
DO - 10.1007/s10787-997-0004-y
M3 - Article
VL - 5
SP - 261
EP - 272
JO - Inflammopharmacology
JF - Inflammopharmacology
SN - 0925-4692
IS - 3
ER -