TY - JOUR
T1 - Fetal cardiac interventricular septum
T2 - Volume assessment by 3D/4D ultrasound using spatio-temporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL)
AU - Rolo, Liliam Cristine
AU - Santana, Eduardo Felix Martins
AU - da Silva, Priscila Henriques
AU - Costa, Fabricio Da Silva
AU - Nardozza, Luciano Marcondes Machado
AU - Tonni, Gabriele
AU - Moron, Antonio Fernandes
AU - Araujo Júnior, Edward
PY - 2015
Y1 - 2015
N2 - Objective: To determine reference values for fetal interventricular septum (IVS) volume by 3D/4D ultrasound using spatio-temporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL). Methods: A prospective cross-sectional study was conducted on 200 consecutive normal low-risk pregnant women at a gestational age ranging from 18w0d to 33w6d. The volume data sets of the fetal heart were acquired by applying STIC to a four-chamber plane. IVS volume was calculated offline using VOCAL with rotation of 30°(six planes). To assess the correlation of fetal IVS volume as a function of gestational age (GA), Pearson's correlation coefficient (r) and polynomial regression models with adjustments through the coefficient of determination (R2) were calculated. The intra-class coefficient (ICC) was used to evaluate intra- and inter-observer reproducibility. Results: A good correlation between GA and fetal IVS volume (r = 0.827) was observed. The mean fetal IVS volume ranged from 0.13 ± 0.03 cm3 (0.08-0.18 cm3) at 18wd0 of gestation to 1.33 ± 0.37 cm3 (0.41-1.98 cm3) at 33w6d. The best correlation between fetal IVS volume and GA was exponential: fetal IVS volume = 0.11e0.139xGA (R2= 0.785). A good intra- and inter-observer reliability were observed, with ICC = 0.999 and 0.991, respectively. Conclusions: Reference values for fetal IVS volume using STIC and VOCAL by 3D/4D ultrasound between 18w0d and 33w6d of gestation were determined and showed to be reliable and concordant.
AB - Objective: To determine reference values for fetal interventricular septum (IVS) volume by 3D/4D ultrasound using spatio-temporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL). Methods: A prospective cross-sectional study was conducted on 200 consecutive normal low-risk pregnant women at a gestational age ranging from 18w0d to 33w6d. The volume data sets of the fetal heart were acquired by applying STIC to a four-chamber plane. IVS volume was calculated offline using VOCAL with rotation of 30°(six planes). To assess the correlation of fetal IVS volume as a function of gestational age (GA), Pearson's correlation coefficient (r) and polynomial regression models with adjustments through the coefficient of determination (R2) were calculated. The intra-class coefficient (ICC) was used to evaluate intra- and inter-observer reproducibility. Results: A good correlation between GA and fetal IVS volume (r = 0.827) was observed. The mean fetal IVS volume ranged from 0.13 ± 0.03 cm3 (0.08-0.18 cm3) at 18wd0 of gestation to 1.33 ± 0.37 cm3 (0.41-1.98 cm3) at 33w6d. The best correlation between fetal IVS volume and GA was exponential: fetal IVS volume = 0.11e0.139xGA (R2= 0.785). A good intra- and inter-observer reliability were observed, with ICC = 0.999 and 0.991, respectively. Conclusions: Reference values for fetal IVS volume using STIC and VOCAL by 3D/4D ultrasound between 18w0d and 33w6d of gestation were determined and showed to be reliable and concordant.
KW - Echocardiography
KW - fetus
KW - interventricular septum
KW - reference value
KW - three-dimensional ultrasound
UR - http://www.scopus.com/inward/record.url?scp=84940774699&partnerID=8YFLogxK
U2 - 10.3109/14767058.2014.955005
DO - 10.3109/14767058.2014.955005
M3 - Article
C2 - 25134922
AN - SCOPUS:84940774699
SN - 1476-7058
VL - 28
SP - 1388
EP - 1393
JO - The Journal of Maternal-Fetal & Neonatal Medicine
JF - The Journal of Maternal-Fetal & Neonatal Medicine
IS - 12
ER -