Fetal and Neonatal Origins of Lung Disease

Foula Sozo, Megan O'Reilly, Richard Harding

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review


Like many organs, the lung can be affected during its period of development in such a way that its later structure and function are altered. This can occur as a result of altered structural development or altered cellular function as a result of genetic or epigenetic alterations. Many such alterations can impair lung function for much or all of the life span and can also increase the risk of later pulmonary illness. Developmental insults or challenges that have the potential to induce persistent alterations in lung structure or function include physical and metabolic changes in the developmental environment.
Original languageEnglish
Title of host publicationStem Cells in the Lung
Subtitle of host publicationDevelopment, Repair and Regeneration
EditorsIvan Bertoncello
Place of PublicationCham Switzerland
PublisherHumana Press
Number of pages32
ISBN (Print)9783319210810
Publication statusPublished - 2015

Publication series

NameStem Cell Biology and Regenerative Medicine
ISSN (Print)2196-8985
ISSN (Electronic)2196-8993

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