Femoral Access and Delivery of Continuous Renal Replacement Therapy Dose

Rinaldo Bellomo, Johan Mårtensson, Serigne Lo, Kirsi-Maija Kaukonen, Alan Cass, Martin Gallagher

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Abstract

Aims: The study aims to describe the use of dialysis catheters in critically ill patients treated with continuous renal replacement therapy (CRRT) and to study the impact of femoral versus non-femoral access on CRRT dose. Methods: Statistical analysis and predictive modelling of data from the Randomized Evaluation of Normal vs. Augmented Level renal replacement therapy trial. Results: The femoral vein was the first access site in 937 (67%) of 1,399 patients. These patients had higher Acute Physiology and Chronic Health Evaluation and Sequential Organ Failure Assessment scores (p = 0.009) and lower pH (p < 0.001) but similar mortality to patients with non-femoral access (44 vs. 45%; p = 0.63). Lower body weight was independently associated with femoral access placement (OR 0.97, 95% CI 0.96-0.98). Femoral access was associated with a 1.03% lower CRRT dose (p = 0.05), but a 4.20% higher dose was achieved with 13.5 Fr catheters (p = 0.03). Conclusions: Femoral access was preferred in lighter and sicker patients. Catheter gauge had greater impact than catheter site in CRRT dose delivery. Video Journal Club "Cappuccino with Claudio Ronco" at http://www.karger.com/?doi=439581.

Original languageEnglish
Pages (from-to)11-17
Number of pages7
JournalBlood Purification
Volume41
Issue number1-3
DOIs
Publication statusPublished - 1 Mar 2016

Keywords

  • Catheters
  • Continuous renal replacement therapy
  • Dialysis
  • Femoral vein
  • Intensive care

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