Females do not have increased risk of early or late mortality after isolated aortic valve replacement: results from a multi-institutional Australian study

Akshat Saxena, Diem Thi Thuy Dinh, Julian Anderson Smith, Christopher Michael Reid, Gilbert Shardey, Andrew Newcomb

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Abstract

There is controversy regarding whether isolated aortic valve replacement (AVR) in women is associated with an increased risk of early and late mortality. The current study evaluates the impact of gender as an independent risk factor for early and late mortality after isolated AVR. Methods: Data obtained between June 2001 and December 2009 by the Australasian Society of Cardiac and Thoracic Surgeons Cardiac Surgery Database Program was retrospectively analysed. Demographic, operative data and postoperative complications were compared between male and female patients using ?2 and t-tests. Long-term survival analysis was performed using Kaplan Meier survival curves and the log rank test. Independent risk factors for short term and long term mortality were identified using binary logistic and Cox regression, respectively. Results: Isolated aortic valve replacement was undertaken for 2790 patients in 18 Australian insitutions; 41.9 were female. Female patients were generally older (mean age 72 vs. 66 years (P
Original languageEnglish
Pages (from-to)297 - 303
Number of pages7
JournalJournal of Cardiovascular Surgery
Volume54
Issue number2
Publication statusPublished - 2013

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