Abstract
Conventional wisdom holds that the ovary and testis are terminally differentiated organs in adult mammals. However, Uhlenhaut et al. (2009) now report that deletion of a single gene, Foxl2, is sufficient to induce transdifferentiation of ovary into testis in adult mice, suggesting that testicular development is actively repressed throughout the life of females.
Original language | English |
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Pages (from-to) | 1051-1053 |
Number of pages | 3 |
Journal | Cell |
Volume | 139 |
Issue number | 6 |
DOIs | |
Publication status | Published - 11 Dec 2009 |
Externally published | Yes |