Females Battle to Suppress Their Inner Male

Andrew Sinclair, Craig Smith

Research output: Contribution to journalShort SurveyResearchpeer-review

11 Citations (Scopus)

Abstract

Conventional wisdom holds that the ovary and testis are terminally differentiated organs in adult mammals. However, Uhlenhaut et al. (2009) now report that deletion of a single gene, Foxl2, is sufficient to induce transdifferentiation of ovary into testis in adult mice, suggesting that testicular development is actively repressed throughout the life of females.

Original languageEnglish
Pages (from-to)1051-1053
Number of pages3
JournalCell
Volume139
Issue number6
DOIs
Publication statusPublished - 11 Dec 2009
Externally publishedYes

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