Both 2D and 3D mathematical models are constructed based on the co-ordinates measurement of a six time enlarged eye model. The graphical image is developed using Pro-E before exported into the COMSOL Multiphysics 3.2. The ocular surface temperature obtained for the 2D model is 33.64°C while the 3D model gives 34.48°C. The 3D model is further simulated for conditions under microwave radiation exposure (750MHz and 1.50GHz). A peak rise in temperature can be observed which agrees well with results from open literatures. These models can be improved by including more complex boundary conditions to simulate the eye to a higher degree of accuracy. The models studied here can be further applied for simulation of diseased eye by specifying proper boundary conditions with the types of diseases. Success of such simulations with appropriate neural network system will provide options for patients with third opinion regarding to the diagnosis of a particular ocular disease.