Feasibility of real-time angiographic perfusion imaging in the treatment of cerebral vasospasm

Christopher Donaldson, Anthea H. O'Neill, Lee-Anne Slater, Winston K. Chong, Leon T. Lai, Ronil V. Chandra

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background:
Objective assessment and quantification of the severity of cerebral vasospasm following aneurysmal subarachnoid hemorrhage is not routinely utilized. We investigated the feasibility of angiographic perfusion imaging derived from digital subtraction angiography (DSA) following endovascular vasospasm treatment procedures.
Methodology:
Real-time blood flow analysis was performed using parametric color coding on pre-and postintervention DSA. Semiquantitative parenchymal perfusion parameters (arrival time [AT] of contrast, time to peak [TTP] opacification, and mean transit time [MTT] of contrast) were calculated across 3 vascular territories (anterior cerebral artery [ACA], middle cerebral artery [MCA], and lenticulostriate arteries) using standard 2-D angiographic perfusion software. The pre-and postintervention arterial vessel diameters were compared.
Original languageEnglish
Pages (from-to)163-169
Number of pages7
JournalInterventional Neurology
Volume6
Issue number3-4
DOIs
Publication statusPublished - 5 Oct 2017

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