Feasibility and Acceptability of a Dietary Intervention to Reduce Salt Intake and Increase High-Nitrate Vegetable Consumption in Malaysian Middle-Aged and Older Adults with Elevated Blood Pressure: Findings from the DePEC-Nutrition Trial

Siew Siew Lee, Andrea McGrattan, Yee Chang Soh, Mawada Alawad, Tin Tin Su, Uma Devi Palanisamy, Azizah Mat Hussin, Zaid Bin Kassim, Ahmad Nizal Bin Mohd Ghazali, Blossom Christa Maree Stephan, Pascale Allotey, Daniel D. Reidpath, Louise Robinson, Devi Mohan, Mario Siervo

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Abstract

The DePEC-Nutrition trial is a complex dietary and behavioural intervention of salt intake reduction combined with increased high-nitrate vegetable consumption among Malaysian middleaged and older adults with elevated blood pressure. This study aimed to assess the feasibility and acceptability of the trial. Participants were recruited from the South East Asia Community Observatory (SEACO) database and randomised into one of four groups: (1) low salt; (2) high-nitrate vegetable; (3) combined high-nitrate vegetable and low salt; and (4) control. The intervention included a combination of group counselling sessions, information booklets, reinforcement videos and text messages to modify dietary behaviour. The primary outcomes evaluated were the measures of feasibility and acceptability of (1) recruitment, follow-up attendance and retention; (2) data collection procedures and clinical outcome measures; and (3) individual and combined multi-modal dietary interventions. A total of 74 participants were recruited, and the 10-month retention rate was 73%. Data collection procedures were acceptable with minimal missing data. All intervention strategies were feasible and acceptable, with group counselling being the most acceptable strategy. This study provides important insights into improving the screening process of participants, facilitating their access to the research facilities and refining the measurement protocols and dietary recommendations, which are instrumental in formulating the design of a full-scale definitive DePEC-Nutrition trial.

Original languageEnglish
Article number430
Number of pages23
JournalNutrients
Volume14
Issue number3
DOIs
Publication statusPublished - Feb 2022

Keywords

  • Dementia
  • Dietary nitrate
  • Feasibility trial
  • Randomised controlled trial
  • Reduced salt

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