Fatty acid binding proteins: potential chaperones of cytosolic drug transport in the enterocyte?

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Abstract

Several poorly water-soluble drugs have previously been shown to bind to intestinal (I-FABP) and liver fatty acid binding protein (L-FABP) in vitro. The purpose of this study was to examine the potential role of drug binding to FABPs on intestinal permeability and gut wall metabolism in vivo.
Original languageEnglish
Pages (from-to)2176-2190
Number of pages15
JournalPharmaceutical Research
Volume28
Issue number9
DOIs
Publication statusPublished - 2011

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