Fatal misuse of codeine-ibuprofen analgesics in Victoria, Australia

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Abstract

Morbidity and mortality in cases where codeine from over-the-counter (OTC) combination analgesics is detected are usually secondary to codeine addiction and are the result of exposure to supratherapeutic doses of simple analgesics containing codeine. Toxicity from the accompanying analgesic, such as paracetamol, ibuprofen or aspirin, can lead to paracetamol hepatotoxicity, or non-steroidal anti-inflammatory drug (NSAID) toxicity such as gastrointestinal ulcers and haemorrhage, or renal tubular acidosis.
Original languageEnglish
Pages (from-to)329 - 331
Number of pages3
JournalMedical Journal of Australia
Volume199
Issue number5
DOIs
Publication statusPublished - 2013

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