TY - JOUR
T1 - Fatal ischemic stroke complicating acute multifocal placoid pigment epitheliopathy
T2 - Histopathological findings
AU - Tsang, Benjamin K T
AU - Chauhan, Devinder S.
AU - Haward, Rebecca
AU - Whiteman, Ida
AU - Frayne, Judith
AU - McLean, Catriona
PY - 2014/3
Y1 - 2014/3
N2 - A previously healthy 29-year-old man was admitted to a tertiary referral center with acute left hemiparesis followed shortly by de novo convulsive status epilepticus. This was in the context of a 2-month history of flu-like symptoms, severe headaches, and retinopathy recently diagnosed as acute multifocal placoid pigment epitheliopathy. Neuroimaging demonstrated bilateral, multiple territory cerebral infarction. Despite intravenous methylprednisolone and craniotomy for the management of raised intracranial pressure, the patient deteriorated and died 14 days later. At autopsy, multiple infarcts of varying ages within a 10-day period were seen in association with a segmental giant cell vasculopathy of meningeal arteries.
AB - A previously healthy 29-year-old man was admitted to a tertiary referral center with acute left hemiparesis followed shortly by de novo convulsive status epilepticus. This was in the context of a 2-month history of flu-like symptoms, severe headaches, and retinopathy recently diagnosed as acute multifocal placoid pigment epitheliopathy. Neuroimaging demonstrated bilateral, multiple territory cerebral infarction. Despite intravenous methylprednisolone and craniotomy for the management of raised intracranial pressure, the patient deteriorated and died 14 days later. At autopsy, multiple infarcts of varying ages within a 10-day period were seen in association with a segmental giant cell vasculopathy of meningeal arteries.
UR - http://www.scopus.com/inward/record.url?scp=84896700757&partnerID=8YFLogxK
U2 - 10.1097/WNO.0b013e318294a4b0
DO - 10.1097/WNO.0b013e318294a4b0
M3 - Article
C2 - 23782929
AN - SCOPUS:84896700757
VL - 34
SP - 10
EP - 15
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
SN - 1070-8022
IS - 1
ER -