Factors associated with the use of prenatal corticosteroids in the management of preterm delivery in Chinese hospitals

Xi Wang, Joshua P. Vogel, Chu-yun Kang, Yan-qiu Gao, Deng Ao, Ru-yan Pang, Yan Wang

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)


Objective: To assess the prevalence of the use of prenatal corticosteroids (PCS) in the management of pretermdeliveryand the factors associated with PCS administration. Methods: A secondary analysis was performed ofa cross-sectional study conducted in 21 Chinese healthcare facilities between November 2010 and January2011. The medical records of women who delivered preterm were reviewed. Associations between PCS administrationand individual and organizational-level factors were determined. Results: The study population comprised659 women who delivered at 20 facilities. PCS were given to 158 (68.1%) of 232 women delivering after27–34 weeks of pregnancy and 119 (27.9%) of 427 delivering after 35–36 weeks. Teenaged girls were less likelyto receive PCS after 27–34 weeks than werewomen aged 20–35 years (odds ratio [OR] 0.22; 95% confidence interval[CI] 0.07–0.70). Amongwomenwho delivered after 35–36 weeks, the odds of receiving PCSwere lower inurban hospitals than in periurban or rural hospitals (OR 0.04; 95% CI 0.00–0.44), and there was significanthospital-level variance with regard to the administration of PCS (P b 0.05). Conclusion: Generally, PCS wereunderprescribed to women at risk of preterm delivery and many women received the treatment after35–36 weeks of pregnancy, when it might not have been effective.
Original languageEnglish
Pages (from-to)260-264
Number of pages5
JournalInternational Journal of Gynecology and Obstetrics
Issue number3
Publication statusPublished - Dec 2014
Externally publishedYes


  • China
  • Multilevel analysis
  • Prenatal corticosteroids
  • Preterm birth

Cite this