TY - JOUR
T1 - Factors associated with stroke among adult patients with hypertension in Ayder Comprehensive Specialized Hospital, Tigray, Ethiopia, 2018
T2 - A case-control study
AU - Mekonen, Haftea Hagos
AU - Birhanu, Mulugeta Molla
AU - Mossie, Tilahun Belete
AU - Gebreslassie, Hagos Tsegabrhan
N1 - Publisher Copyright:
© 2020 Mekonen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2020/2/13
Y1 - 2020/2/13
N2 - Background Globally, the burden of stroke is increasing at an alarming rate. Factors associated with stroke among hypertensive patients are not consistent across different studies and there are limited studies particularly to hypertensive stroke in the particular setting. This study aimed to assess factors associated with stroke among patients with hypertension in Ayder Comprehensive Specialized Hospital, Mekelle, Tigray, Ethiopia, in 2018. Methods Hospital-based case-control study was conducted from February to April 2018. Cases were adult hypertensive patients with stroke and controls were adult hypertensive patients without a stroke. Cases and controls were identified from the patient’s card review. Using a systematic random sampling technique 89 cases and 356 controls were included in this study. Record review, physical measurement, and interview techniques were used to collect data. Data was entered and analyzed by using SPSS version 23. Variables with a p-value of less than 0.25 in the bivariate logistic regression were selected for multivariable logistic regression. The adjusted odds ratio and 95% confidence interval were used to determine the association. P-value <0.05 was used to declare statistical significance. Results The mean age of cases and controls were 56.3 years (SD±13.53) and 51.9 years (SD ±12.67) respectively. Lost to follow-up (AOR = 2.474, 95%CI: 1.368–4.929), alcohol drinking (AOR = 2.440, 95%CI: 1.291–4.613), use of excessive salt in diet (AOR = 3.249, 95%CI: (1.544–6.837), medication non-adherence (AOR = 3.967, 95%CI: 2.256–6.973), uncontrolled systolic blood pressure, (AOR = 3.196, 95%CI: 1.60–6.382), uncontrolled diastolic blood pressure (AOR = 2.204, 95%CI: 1.130–4.297) and high cholesterol level (AOR = 2.413, 95%CI: 1.319–4.414) were found to be significant factors. Conclusion Lost to follow-up, alcohol drinking, uses of excessive salt in diet, medication non-adherence, and uncontrolled systolic and diastolic blood pressure were associated with stroke. Health education on lifestyle practices and hypertension-related complications in each follow-up visit is very essential for improving the primary stroke prevention.
AB - Background Globally, the burden of stroke is increasing at an alarming rate. Factors associated with stroke among hypertensive patients are not consistent across different studies and there are limited studies particularly to hypertensive stroke in the particular setting. This study aimed to assess factors associated with stroke among patients with hypertension in Ayder Comprehensive Specialized Hospital, Mekelle, Tigray, Ethiopia, in 2018. Methods Hospital-based case-control study was conducted from February to April 2018. Cases were adult hypertensive patients with stroke and controls were adult hypertensive patients without a stroke. Cases and controls were identified from the patient’s card review. Using a systematic random sampling technique 89 cases and 356 controls were included in this study. Record review, physical measurement, and interview techniques were used to collect data. Data was entered and analyzed by using SPSS version 23. Variables with a p-value of less than 0.25 in the bivariate logistic regression were selected for multivariable logistic regression. The adjusted odds ratio and 95% confidence interval were used to determine the association. P-value <0.05 was used to declare statistical significance. Results The mean age of cases and controls were 56.3 years (SD±13.53) and 51.9 years (SD ±12.67) respectively. Lost to follow-up (AOR = 2.474, 95%CI: 1.368–4.929), alcohol drinking (AOR = 2.440, 95%CI: 1.291–4.613), use of excessive salt in diet (AOR = 3.249, 95%CI: (1.544–6.837), medication non-adherence (AOR = 3.967, 95%CI: 2.256–6.973), uncontrolled systolic blood pressure, (AOR = 3.196, 95%CI: 1.60–6.382), uncontrolled diastolic blood pressure (AOR = 2.204, 95%CI: 1.130–4.297) and high cholesterol level (AOR = 2.413, 95%CI: 1.319–4.414) were found to be significant factors. Conclusion Lost to follow-up, alcohol drinking, uses of excessive salt in diet, medication non-adherence, and uncontrolled systolic and diastolic blood pressure were associated with stroke. Health education on lifestyle practices and hypertension-related complications in each follow-up visit is very essential for improving the primary stroke prevention.
UR - https://www.scopus.com/pages/publications/85079338698
U2 - 10.1371/journal.pone.0228650
DO - 10.1371/journal.pone.0228650
M3 - Article
C2 - 32053644
AN - SCOPUS:85079338698
SN - 1932-6203
VL - 15
JO - PLoS ONE
JF - PLoS ONE
IS - 2
M1 - e0228650
ER -