Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex

Tatiana Petrova; Holger Steuber; Isabelle Hazemann; Alexandra Cousido-Siah; Andre Mitschler; Roland Poh-Tuck Chung; Mitsuru Oka; Gerhard Klebe; Ossama El-Kabbani; Andrzej Joachimiak; Alberto D Podjarny

doi:10.1021/jm050424

Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex

Tatiana Petrova, Holger Steuber, Isabelle Hazemann, Alexandra Cousido-Siah, Andre Mitschler, Roland Poh-Tuck Chung, Mitsuru Oka, Gerhard Klebe, Ossama El-Kabbani, Andrzej Joachimiak, Alberto D Podjarny

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

57 Citations (Scopus)

Abstract

Photocopy or offprint of article

Original language	English
Pages (from-to)	5659 - 5665
Number of pages	7
Journal	Journal of Medicinal Chemistry
Volume	48
Issue number	18
DOIs	https://doi.org/10.1021/jm050424
Publication status	Published - 2005

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10.1021/jm050424

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Petrova, T., Steuber, H., Hazemann, I., Cousido-Siah, A., Mitschler, A., Chung, R. P.-T., Oka, M., Klebe, G., El-Kabbani, O., Joachimiak, A., & Podjarny, A. D. (2005). Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex. Journal of Medicinal Chemistry, 48(18), 5659 - 5665. https://doi.org/10.1021/jm050424

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title = "Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex",

abstract = "Photocopy or offprint of article",

author = "Tatiana Petrova and Holger Steuber and Isabelle Hazemann and Alexandra Cousido-Siah and Andre Mitschler and Chung, {Roland Poh-Tuck} and Mitsuru Oka and Gerhard Klebe and Ossama El-Kabbani and Andrzej Joachimiak and Podjarny, {Alberto D}",

year = "2005",

doi = "10.1021/jm050424",

language = "English",

volume = "48",

pages = "5659 -- 5665",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

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Petrova, T, Steuber, H, Hazemann, I, Cousido-Siah, A, Mitschler, A, Chung, RP-T, Oka, M, Klebe, G, El-Kabbani, O, Joachimiak, A & Podjarny, AD 2005, 'Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex', Journal of Medicinal Chemistry, vol. 48, no. 18, pp. 5659 - 5665. https://doi.org/10.1021/jm050424

Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex. / Petrova, Tatiana; Steuber, Holger; Hazemann, Isabelle et al.
In: Journal of Medicinal Chemistry, Vol. 48, No. 18, 2005, p. 5659 - 5665.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex

AU - Petrova, Tatiana

AU - Steuber, Holger

AU - Hazemann, Isabelle

AU - Cousido-Siah, Alexandra

AU - Mitschler, Andre

AU - Chung, Roland Poh-Tuck

AU - Oka, Mitsuru

AU - Klebe, Gerhard

AU - El-Kabbani, Ossama

AU - Joachimiak, Andrzej

AU - Podjarny, Alberto D

PY - 2005

Y1 - 2005

N2 - Photocopy or offprint of article

AB - Photocopy or offprint of article

UR - http://pubs3.acs.org/acs/journals/toc.page?incoden=jmcmar

U2 - 10.1021/jm050424

DO - 10.1021/jm050424

M3 - Article

SN - 0022-2623

VL - 48

SP - 5659

EP - 5665

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 18

ER -

Factorizing selectivity determinants of inhibitor binding toward aldose and aldehyde reductases: Structural and thermodynamic properties of the aldose reductase mutant Leu300Pro-fidarestat complex

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