Facile preparation of 2-arylbenzoselenazoles from three components reactions: 2-Chloronitrobenzene, Se, and arylacetic acids

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A selenium-mediated decarboxylative cyclization of 2-chloronitrobenzene and arylacetic acids to prepare 2-arylbenzoselenazoles has been established under metal-free condition. The reactions proceeded in moderate to good yields with good functional tolerance and gram-scale application.

Original languageEnglish
Article number151393
Number of pages4
JournalTetrahedron Letters
Issue number3
Publication statusPublished - 16 Jan 2020


  • Arylacetic acid
  • Benzoselenazoles
  • Cyclization
  • Selenium powder

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