Abstract
Optimised monomer feed ratios in the spontaneous zwitterionic copolymerisation (SZWIP) of 2-oxazolines and acrylic acid enable the one-step synthesis of heterotelechelic α-acrylate, ω-carboxylic acid N-acylated poly(aminoester) macromonomers. Subsequent redox-initiated RAFT polymerisation at ambient temperature leads to comb polymers containing quantitative terminal side chain carboxylic acids, which allow efficient 'grafting-onto' using conventional peptide coupling strategies.
| Original language | English |
|---|---|
| Pages (from-to) | 6703-6707 |
| Number of pages | 5 |
| Journal | Polymer Chemistry |
| Volume | 7 |
| Issue number | 44 |
| DOIs | |
| Publication status | Published - 28 Nov 2016 |
Cite this
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Facile one-pot/one-step synthesis of heterotelechelic : N-acylated poly(aminoester) macromonomers for carboxylic acid decorated comb polymers. / de Jongh, Patrick A. J. M.; Bennett, Mechelle R.; Sulley, Greg S.; Wilson, Paul; Davis, Thomas P.; Haddleton, David M.; Kempe, Kristian.
In: Polymer Chemistry, Vol. 7, No. 44, 28.11.2016, p. 6703-6707.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Facile one-pot/one-step synthesis of heterotelechelic
T2 - N-acylated poly(aminoester) macromonomers for carboxylic acid decorated comb polymers
AU - de Jongh, Patrick A. J. M.
AU - Bennett, Mechelle R.
AU - Sulley, Greg S.
AU - Wilson, Paul
AU - Davis, Thomas P.
AU - Haddleton, David M.
AU - Kempe, Kristian
PY - 2016/11/28
Y1 - 2016/11/28
N2 - Optimised monomer feed ratios in the spontaneous zwitterionic copolymerisation (SZWIP) of 2-oxazolines and acrylic acid enable the one-step synthesis of heterotelechelic α-acrylate, ω-carboxylic acid N-acylated poly(aminoester) macromonomers. Subsequent redox-initiated RAFT polymerisation at ambient temperature leads to comb polymers containing quantitative terminal side chain carboxylic acids, which allow efficient 'grafting-onto' using conventional peptide coupling strategies.
AB - Optimised monomer feed ratios in the spontaneous zwitterionic copolymerisation (SZWIP) of 2-oxazolines and acrylic acid enable the one-step synthesis of heterotelechelic α-acrylate, ω-carboxylic acid N-acylated poly(aminoester) macromonomers. Subsequent redox-initiated RAFT polymerisation at ambient temperature leads to comb polymers containing quantitative terminal side chain carboxylic acids, which allow efficient 'grafting-onto' using conventional peptide coupling strategies.
UR - http://www.scopus.com/inward/record.url?scp=84994493228&partnerID=8YFLogxK
U2 - 10.1039/c6py01553k
DO - 10.1039/c6py01553k
M3 - Article
VL - 7
SP - 6703
EP - 6707
JO - Polymer Chemistry
JF - Polymer Chemistry
SN - 1759-9954
IS - 44
ER -