Fabrication of mechanically tissue-like fibrous poly(xylitol sebacate) using core/shell electrospinning technique

Yuan Li; Qizhi Chen

doi:10.1002/adem.201400230

Fabrication of mechanically tissue-like fibrous poly(xylitol sebacate) using core/shell electrospinning technique

Yuan Li, Qizhi Chen

Materials Science & Engineering

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Abstract

Chemically crosslinked elastomer poly(xylitol sebacate)(PXS) is for the first time electrospun into fibrous mats. The PXS2:5 fibre mats show nonlinear J-shaped stress-strain curves, with large average rupture elongation (≈75%). The newly developed porous PXS scaffolds show tissue-like mechanical properties and excellent biocompatibility, making them very promising for bioengineering of very soft tissues and organs.

Original language	English
Pages (from-to)	324 - 329
Number of pages	6
Journal	Advanced Engineering Materials
Volume	17
Issue number	3
DOIs	https://doi.org/10.1002/adem.201400230
Publication status	Published - 2015

Keywords

Scaffolds (biology)
Biocompatibility
Biomechanics
Mechanical properties
Stress-strain curves
Sugar substitutes
Tissue Core/shell
Cross-linked elastomers
Electrospinning techniques
Fibre mats
Sebacate
Very soft tissue

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10.1002/adem.201400230

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@article{39781f336b4e4eaba495c2af00fa0871,

title = "Fabrication of mechanically tissue-like fibrous poly(xylitol sebacate) using core/shell electrospinning technique",

abstract = "Chemically crosslinked elastomer poly(xylitol sebacate)(PXS) is for the first time electrospun into fibrous mats. The PXS2:5 fibre mats show nonlinear J-shaped stress-strain curves, with large average rupture elongation (≈75%). The newly developed porous PXS scaffolds show tissue-like mechanical properties and excellent biocompatibility, making them very promising for bioengineering of very soft tissues and organs.",

keywords = "Scaffolds (biology), Biocompatibility, Biomechanics, Mechanical properties, Stress-strain curves, Sugar substitutes, Tissue Core/shell, Cross-linked elastomers, Electrospinning techniques, Fibre mats, Sebacate, Very soft tissue",

author = "Yuan Li and Qizhi Chen",

year = "2015",

doi = "10.1002/adem.201400230",

language = "English",

volume = "17",

pages = "324 -- 329",

journal = "Advanced Engineering Materials",

issn = "1438-1656",

publisher = "Wiley-VCH Verlag GmbH & Co. KGaA",

number = "3",

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T1 - Fabrication of mechanically tissue-like fibrous poly(xylitol sebacate) using core/shell electrospinning technique

AU - Li, Yuan

AU - Chen, Qizhi

PY - 2015

Y1 - 2015

N2 - Chemically crosslinked elastomer poly(xylitol sebacate)(PXS) is for the first time electrospun into fibrous mats. The PXS2:5 fibre mats show nonlinear J-shaped stress-strain curves, with large average rupture elongation (≈75%). The newly developed porous PXS scaffolds show tissue-like mechanical properties and excellent biocompatibility, making them very promising for bioengineering of very soft tissues and organs.

AB - Chemically crosslinked elastomer poly(xylitol sebacate)(PXS) is for the first time electrospun into fibrous mats. The PXS2:5 fibre mats show nonlinear J-shaped stress-strain curves, with large average rupture elongation (≈75%). The newly developed porous PXS scaffolds show tissue-like mechanical properties and excellent biocompatibility, making them very promising for bioengineering of very soft tissues and organs.

KW - Scaffolds (biology)

KW - Biocompatibility

KW - Biomechanics

KW - Mechanical properties

KW - Stress-strain curves

KW - Sugar substitutes

KW - Tissue Core/shell

KW - Cross-linked elastomers

KW - Electrospinning techniques

KW - Fibre mats

KW - Sebacate

KW - Very soft tissue

UR - http://onlinelibrary.wiley.com/doi/10.1002/adem.201400230/epdf

U2 - 10.1002/adem.201400230

DO - 10.1002/adem.201400230

M3 - Article

SN - 1438-1656

VL - 17

SP - 324

EP - 329

JO - Advanced Engineering Materials

JF - Advanced Engineering Materials

IS - 3

ER -

Fabrication of mechanically tissue-like fibrous poly(xylitol sebacate) using core/shell electrospinning technique

Abstract

Keywords

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