Fabrication of cysteine-responsive biomimetic single nanochannels by a thiol-yne reaction strategy and their application for sensing in urine samples

Zhongyue Sun, Cuiping Han, Miaomiao Song, Long Wen, Demei Tian, Haibing Li, Lei Jiang

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)


A photoinitiated thiol-yne click reaction strategy is used to fabricate a novel responsive biomimetic nanochannel platform. It displays a selective response for Cys by way of covalent bond formation on the channel surface. This system can be applied for Cys sensing with high specificity and non-interference performance in complex matrices and human urine samples.

Original languageEnglish
Pages (from-to)455-460
Number of pages6
JournalAdvanced Materials
Issue number3
Publication statusPublished - 22 Jan 2014
Externally publishedYes


  • biomimetics
  • biosensors
  • cysteine
  • single nanochannels
  • thiol-yne click reaction

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