Fabrication of boron nitride nanotube-gold nanoparticle hybrids using pulsed plasma in liquid

Sri Balaji Ponraj, Zhiqiang Chen, Lu Hua Li, Jayanth Suryanarayanan Shankaranarayanan, Gayathri Devi Rajmohan, Johan Du Plessis, Andrew J. Sinclair, Ying Chen, Xungai Wang, Jagat R. Kanwar, Xiujuan J. Dai

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Plasma, generated in liquid at atmospheric pressure by a nanosecond pulsed voltage, was used to fabricate hybrid structures from boron nitride nanotubes and gold nanoparticles in deionized water. The pH was greatly reduced, conductivity was significantly increased, and concentrations of reactive oxygen and nitrogen species in the water were increased by the plasma treatment. The treatment reduced the length of the nanotubes, giving more individual cuplike structures, and introduced functional groups onto the surface. Gold nanoparticles were successively assembled onto the functionalized surfaces. The reactive species from the liquid plasma along with the nanosecond pulsed electric field seem to play a role in the shortening and functionalization of the nanotubes and the assembly of gold nanoparticles. The potential for targeted drug delivery was tested in a preliminary investigation using doxorubicin-loaded plasma-treated nanotubes which were effective at killing ∼99% of prostate cancer cells.

Original languageEnglish
Pages (from-to)10712-10720
Number of pages9
Issue number35
Publication statusPublished - 9 Sept 2014
Externally publishedYes

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