Extraction of phytochemicals using hydrotropic solvents

Jayesree Nagarajan, Wong Wah Heng, Charis M. Galanakis, Ramakrishnan Nagasundara Ramanan, Mavinakere Eshwaraiah Raghunandan, Jian Sun, Amin Ismail, Tey Beng-Ti, Krishnamurthy Nagendra Prasad

    Research output: Contribution to journalReview ArticleResearchpeer-review

    21 Citations (Scopus)


    ABSTRACT: Every plant synthesizes phytochemicals with different properties to supply a pool of molecules for food, chemical and pharmaceutical applications. Concurrent with “green technology” development, use of green solvents to extract phytochemicals instead of conventional non-eco-friendly solvents is crucial. Hydrotrope is a one of the green solvents that enhances solubility of poorly water-soluble or hydrophobic compounds in aqueous solutions. This article critically reviews the extraction of phytochemicals using various hydrotropic solvents. Hydrotropy mechanisms, factors influencing extraction and recovery methods of phytochemicals were also evaluated in this review.

    Original languageEnglish
    Pages (from-to)1151-1165
    Number of pages15
    JournalSeparation Science and Technology
    Issue number7
    Publication statusPublished - 29 Apr 2016


    • Hydrotropes
    • mechanism
    • phytochemicals
    • recovery

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