Projects per year
Background It's unclear whether exposures to low-level air pollution have adverse effects on birth outcomes, and which trimester-specific pregnant exposure is sensitive. Objectives To investigate the effects of maternal exposure during each trimester and the whole pregnancy to particles with aerodynamic diameter < 2.5 μm (PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) on preterm birth (PTB) and low birth weight (LBW). Methods Daily data on birth records, air quality, and weather conditions were collected in Brisbane, Australia during 2003–2013. Mean concentrations of air pollutants were calculated for each trimester of pregnancy. Cox proportional hazards models were used to examine the associations between air pollution and birth outcomes. Multi-pollutant models and stratified analyses by ambient temperature were performed. Results Exposures to PM2.5, SO2, NO2, and O3 during the whole pregnancy were associated with increased risk of PTB [IQR HRs (hazard ratios with an interquartile range increase in air pollutants) and 95% confidence intervals (CIs): 1.05 (1.02, 1.08), 1.12 (1.09, 1.16), 1.07 (1.01, 1.13), and 1.13 (1.10, 1.16), respectively] and LBW [IQR HRs and 95% CIs: 1.06 (1.02, 1.10), 1.12 (1.08, 1.16), 1.11 (1.03, 1.18), and 1.13 (1.09, 1.17), respectively]. Highest HRs were observed during trimester 3, and lowest in trimester 1. For each air pollutant, stronger effects on PTB and LBW were present for exposure to low and moderate temperatures than exposure to high ambient temperature. Conclusions Exposures to low-level air pollutants are related to adverse birth outcomes. More effective policies for air quality control could contribute to improving neonatal health.
|Number of pages||6|
|Journal||Science of the Total Environment|
|Publication status||Published - 1 May 2018|
- Air pollution
- Hazard ratio
- Low birth weight
- Preterm birth
NHMRC Centre for Air quality and health Research and evaluation (CAR) Seed Funding - Estimating air pollution exposure and its health effects in China
Li, S., Guo, Y., Abramson, M., Williams, G. M., Ren, H. & Dong, G.
17/07/17 → 31/12/17
Environmental exposure, human behaviour and respiratory health for children with asthma.
1/03/17 → 31/12/21
Advancing the assessment of environmental impacts on human health
1/03/17 → 31/12/18