Expert voices and equal partnerships: establishing controlled human infection models (CHIMs) in Vietnam

OUCRU Controlled Human Infection Models workshop and focus group participants

doi:10.12688/wellcomeopenres.15337.1

Expert voices and equal partnerships: establishing controlled human infection models (CHIMs) in Vietnam

OUCRU Controlled Human Infection Models workshop and focus group participants

Research output: Contribution to journal › Article › Other › peer-review

10 Citations (Scopus)

Abstract

The number of controlled human infection models (CHIMs) conducted worldwide has increased considerably in recent years, although few have been conducted in low and middle-income countries (LMICs), where infectious diseases have the greatest burden. Recently Oxford University Clinical Research Unit (OUCRU) in Ho Chi Minh City (HCMC) started developing CHIM research proposals motivated by the need to develop a clearer and more grounded understanding of the issues surrounding the conduct of CHIMs in LMICs. To explore initial perceptions and barriers to conducting CHIMs in Vietnam, OUCRU researchers conducted a set of key stakeholder interviews early in 2018 and held a CHIM workshop in HCMC in March 2018. This paper summarizes the discussions from the workshop and outlines a way forward for conducting CHIMs in Vietnam.

Original language	English
Article number	143
Number of pages	12
Journal	Wellcome Open Research
Volume	4
DOIs	https://doi.org/10.12688/wellcomeopenres.15337.1
Publication status	Published - 2019

Keywords

CHIM
Controlled human infection model
Human challenge studies
Vaccine
Workshop report

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.12688/wellcomeopenres.15337.1

301346067-oaFinal published version, 910 KB

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title = "Expert voices and equal partnerships: establishing controlled human infection models (CHIMs) in Vietnam",

abstract = "The number of controlled human infection models (CHIMs) conducted worldwide has increased considerably in recent years, although few have been conducted in low and middle-income countries (LMICs), where infectious diseases have the greatest burden. Recently Oxford University Clinical Research Unit (OUCRU) in Ho Chi Minh City (HCMC) started developing CHIM research proposals motivated by the need to develop a clearer and more grounded understanding of the issues surrounding the conduct of CHIMs in LMICs. To explore initial perceptions and barriers to conducting CHIMs in Vietnam, OUCRU researchers conducted a set of key stakeholder interviews early in 2018 and held a CHIM workshop in HCMC in March 2018. This paper summarizes the discussions from the workshop and outlines a way forward for conducting CHIMs in Vietnam.",

keywords = "CHIM, Controlled human infection model, Human challenge studies, Vaccine, Workshop report",

author = "Evelyne Kestelyn and Phuong, {Chi Le} and {Van Nuil}, {Jennifer Ilo} and {Dong Thi}, {Hoai Tam} and Nguyen, {Nguyet Minh} and {Dinh The}, Trung and Mary Chambers and Simmons, {Cameron P.} and Trong, {Toan Nguyen} and The, {Dung Nguyen} and Phuong, {Le Truc} and Van, {Dung Do} and Anh, {Dung Duc} and {Nguyen Van}, {Vinh Chau} and Stephen Baker and Bridget Wills and {OUCRU Controlled Human Infection Models workshop and focus group participants}",

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AU - Kestelyn, Evelyne

AU - Phuong, Chi Le

AU - Van Nuil, Jennifer Ilo

AU - Dong Thi, Hoai Tam

AU - Nguyen, Nguyet Minh

AU - Dinh The, Trung

AU - Chambers, Mary

AU - Simmons, Cameron P.

AU - Trong, Toan Nguyen

AU - The, Dung Nguyen

AU - Phuong, Le Truc

AU - Van, Dung Do

AU - Anh, Dung Duc

AU - Nguyen Van, Vinh Chau

AU - Baker, Stephen

AU - Wills, Bridget

AU - OUCRU Controlled Human Infection Models workshop and focus group participants

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AB - The number of controlled human infection models (CHIMs) conducted worldwide has increased considerably in recent years, although few have been conducted in low and middle-income countries (LMICs), where infectious diseases have the greatest burden. Recently Oxford University Clinical Research Unit (OUCRU) in Ho Chi Minh City (HCMC) started developing CHIM research proposals motivated by the need to develop a clearer and more grounded understanding of the issues surrounding the conduct of CHIMs in LMICs. To explore initial perceptions and barriers to conducting CHIMs in Vietnam, OUCRU researchers conducted a set of key stakeholder interviews early in 2018 and held a CHIM workshop in HCMC in March 2018. This paper summarizes the discussions from the workshop and outlines a way forward for conducting CHIMs in Vietnam.

KW - CHIM

KW - Controlled human infection model

KW - Human challenge studies

KW - Vaccine

KW - Workshop report

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JO - Wellcome Open Research

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M1 - 143

ER -

Expert voices and equal partnerships: establishing controlled human infection models (CHIMs) in Vietnam

Abstract

Keywords

UN SDGs

Access to Document

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