TY - JOUR
T1 - Experimental autoimmune uveoretinitis
T2 - A model system for immunointervention: Review
AU - Forrester, J. V.
AU - Liversidge, Janet
AU - Dua, H. S.
AU - Dick, A.
AU - Harper, Fiona
AU - Mcmenamin, P. G.
PY - 1992/1/1
Y1 - 1992/1/1
N2 - Experimental autoimmune uveoretinitis (EAU) is a useful model of human posterior uveitis and as such, permits the analysis of strategies for immuno-intervention. Modulation of the autoimmune response may be attempted at the stages of induction of EAU, during homing of autoreactive lymphocytes to the target organ, the retina, or during the effector stage of the disease. This paper presents a brief overview of current immuno-therapeutic modalities and assesses the usefulness for extrapolation to human disease.
AB - Experimental autoimmune uveoretinitis (EAU) is a useful model of human posterior uveitis and as such, permits the analysis of strategies for immuno-intervention. Modulation of the autoimmune response may be attempted at the stages of induction of EAU, during homing of autoreactive lymphocytes to the target organ, the retina, or during the effector stage of the disease. This paper presents a brief overview of current immuno-therapeutic modalities and assesses the usefulness for extrapolation to human disease.
UR - http://www.scopus.com/inward/record.url?scp=0026699173&partnerID=8YFLogxK
U2 - 10.3109/02713689208999509
DO - 10.3109/02713689208999509
M3 - Review Article
C2 - 1358557
AN - SCOPUS:0026699173
SN - 0271-3683
VL - 11
SP - 33
EP - 40
JO - Current Eye Research
JF - Current Eye Research
IS - S1
ER -