Experimental autoimmune uveoretinitis: A model system for immunointervention: Review

J. V. Forrester, Janet Liversidge, H. S. Dua, A. Dick, Fiona Harper, P. G. Mcmenamin

Research output: Contribution to journalReview ArticleResearchpeer-review

70 Citations (Scopus)

Abstract

Experimental autoimmune uveoretinitis (EAU) is a useful model of human posterior uveitis and as such, permits the analysis of strategies for immuno-intervention. Modulation of the autoimmune response may be attempted at the stages of induction of EAU, during homing of autoreactive lymphocytes to the target organ, the retina, or during the effector stage of the disease. This paper presents a brief overview of current immuno-therapeutic modalities and assesses the usefulness for extrapolation to human disease.

Original languageEnglish
Pages (from-to)33-40
Number of pages8
JournalCurrent Eye Research
Volume11
Issue numberS1
DOIs
Publication statusPublished - 1 Jan 1992
Externally publishedYes

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