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Expansion and preservation of multipotentiality of rabbit bone-marrow derived mesenchymal stem cells in dextran-based microcarrier spin culture

  • Lily Boo
  • , Lakshmi Selvaratnam
  • , Cheh Chin Tai
  • , T S Ahmad
  • , Tunku Kamarul

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The use of mesenchymal stem cells (MSCs) in tissue repair and regeneration despite their multipotentiality has been limited by their cell source quantity and decelerating proliferative yield efficiency. A study was thus undertaken to determine the feasibility of using microcarrier beads in spinner flask cultures for MSCs expansion and compared to that of conventional monolayer cultures and static microcarrier cultures
Original languageEnglish
Pages (from-to)1343 - 1356
Number of pages14
JournalJournal of Materials Science: Materials in Medicine
Volume22
Issue number5
DOIs
Publication statusPublished - 2011

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