Excess stroke incidence in young Aboriginal people in South Australia

Pooled results from two population-based studies

Anna H. Balabanski, Jonathan Newbury, James M. Leyden, Hisatomi Arima, Craig S. Anderson, Sally Castle, Jennifer Cranefield, Tracey Paterson, Amanda G. Thrift, Judith Katzenellenbogen, Alex Brown, Timothy J. Kleinig

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective “ideal” South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009–2010) and SEARCH in five South Australian rural centers (2009–2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95–137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51–84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2–7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4–61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities.

Original languageEnglish
Pages (from-to)811-814
Number of pages4
JournalInternational Journal of Stroke
Volume13
Issue number8
DOIs
Publication statusPublished - Oct 2018

Keywords

  • Aboriginal
  • epidemiology
  • hemorrhagic stroke
  • ischemic stroke
  • Stroke

Cite this

Balabanski, A. H., Newbury, J., Leyden, J. M., Arima, H., Anderson, C. S., Castle, S., ... Kleinig, T. J. (2018). Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studies. International Journal of Stroke, 13(8), 811-814. https://doi.org/10.1177/1747493018778113
Balabanski, Anna H. ; Newbury, Jonathan ; Leyden, James M. ; Arima, Hisatomi ; Anderson, Craig S. ; Castle, Sally ; Cranefield, Jennifer ; Paterson, Tracey ; Thrift, Amanda G. ; Katzenellenbogen, Judith ; Brown, Alex ; Kleinig, Timothy J. / Excess stroke incidence in young Aboriginal people in South Australia : Pooled results from two population-based studies. In: International Journal of Stroke. 2018 ; Vol. 13, No. 8. pp. 811-814.
@article{1467e3d398754d8dbbb7803c16078eaf,
title = "Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studies",
abstract = "Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective “ideal” South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009–2010) and SEARCH in five South Australian rural centers (2009–2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95{\%} CI: 95–137) was nearly two-fold that of non-Aboriginal patients (67, 95{\%} CI: 51–84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95{\%} CI: 2–7), particularly for intracerebral hemorrhage (IRR: 16, 95{\%} CI: 4–61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities.",
keywords = "Aboriginal, epidemiology, hemorrhagic stroke, ischemic stroke, Stroke",
author = "Balabanski, {Anna H.} and Jonathan Newbury and Leyden, {James M.} and Hisatomi Arima and Anderson, {Craig S.} and Sally Castle and Jennifer Cranefield and Tracey Paterson and Thrift, {Amanda G.} and Judith Katzenellenbogen and Alex Brown and Kleinig, {Timothy J.}",
year = "2018",
month = "10",
doi = "10.1177/1747493018778113",
language = "English",
volume = "13",
pages = "811--814",
journal = "International Journal of Stroke",
issn = "1747-4930",
publisher = "Wiley-Blackwell",
number = "8",

}

Balabanski, AH, Newbury, J, Leyden, JM, Arima, H, Anderson, CS, Castle, S, Cranefield, J, Paterson, T, Thrift, AG, Katzenellenbogen, J, Brown, A & Kleinig, TJ 2018, 'Excess stroke incidence in young Aboriginal people in South Australia: Pooled results from two population-based studies', International Journal of Stroke, vol. 13, no. 8, pp. 811-814. https://doi.org/10.1177/1747493018778113

Excess stroke incidence in young Aboriginal people in South Australia : Pooled results from two population-based studies. / Balabanski, Anna H.; Newbury, Jonathan; Leyden, James M.; Arima, Hisatomi; Anderson, Craig S.; Castle, Sally; Cranefield, Jennifer; Paterson, Tracey; Thrift, Amanda G.; Katzenellenbogen, Judith; Brown, Alex; Kleinig, Timothy J.

In: International Journal of Stroke, Vol. 13, No. 8, 10.2018, p. 811-814.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Excess stroke incidence in young Aboriginal people in South Australia

T2 - Pooled results from two population-based studies

AU - Balabanski, Anna H.

AU - Newbury, Jonathan

AU - Leyden, James M.

AU - Arima, Hisatomi

AU - Anderson, Craig S.

AU - Castle, Sally

AU - Cranefield, Jennifer

AU - Paterson, Tracey

AU - Thrift, Amanda G.

AU - Katzenellenbogen, Judith

AU - Brown, Alex

AU - Kleinig, Timothy J.

PY - 2018/10

Y1 - 2018/10

N2 - Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective “ideal” South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009–2010) and SEARCH in five South Australian rural centers (2009–2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95–137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51–84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2–7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4–61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities.

AB - Background: Retrospective data indicate increased stroke incidence in Aboriginal/Torres Strait Islander (Indigenous) Australians, possibly with poorer outcomes. We present the first prospective population-based stroke incidence study in Indigenous Australians. Methods: We pooled data from ASCEND and SEARCH, two prospective “ideal” South Australian stroke incidence studies, ASCEND conducted in urban Northwestern Adelaide (2009–2010) and SEARCH in five South Australian rural centers (2009–2011). We calculated age-standardized incidence for Aboriginal and non-Aboriginal people. Results: The study population comprised 261,403 inhabitants. Among 432 first-ever strokes, 13 were in Aboriginal people (median age 51 vs. 78 years for non-Aboriginal people, p < 0.001). Age-standardized stroke incidence per 100,000 in Aboriginal patients (116, 95% CI: 95–137) was nearly two-fold that of non-Aboriginal patients (67, 95% CI: 51–84). Age-stratified excess incidence in Aboriginal people was restricted to those aged < 55 years (incidence rate ratio (IRR) 3.5, 95% CI: 2–7), particularly for intracerebral hemorrhage (IRR: 16, 95% CI: 4–61). Conclusion: The excess stroke incidence in Aboriginal South Australians appears substantial, especially in those aged <55 years. Further work is required to delineate and address disparities.

KW - Aboriginal

KW - epidemiology

KW - hemorrhagic stroke

KW - ischemic stroke

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=85047402297&partnerID=8YFLogxK

U2 - 10.1177/1747493018778113

DO - 10.1177/1747493018778113

M3 - Article

VL - 13

SP - 811

EP - 814

JO - International Journal of Stroke

JF - International Journal of Stroke

SN - 1747-4930

IS - 8

ER -