TY - JOUR
T1 - Examining diagnostic value of the fasting plasma glucose in screening gestational diabetes
AU - Mirfeizi, Mani
AU - Toorzani, Zahra Mehdizadeh
AU - Jafarabadi, Mohammad Asghari
AU - Shoghi, Mahnaz
AU - Gholami, Mohammad Javad
AU - Tekmehdash, Ali Moniri
PY - 2011
Y1 - 2011
N2 - Background: Many different tests have been introduced for screening gestational diabetes mellitus (GDM). The Objectives of this study were to determine both the diagnostic value of fasting plasma glucose (FPG) and the suitable cut-off point of plasma glucose with the best sensitivity and specificity for diagnosing gestational diabetes mellitus (GDM). Methods: This cross-sectional study was done on 242 women in Karaj-Iran who had at least one risk factor for GDM. Having conducted 50 gram glucose challenge test (GCT), the diagnostic values of FPG were determined by receiver operating characteristic curve (ROC). Then the level of plasma glucose, with the highest sensitivity and specificity rate, were determined for the diagnosis of GDM. Results: Based on the results of ROC curve, FPG with cut-off point ≥91 mg/dl revealed 63.89% and 76.56% sensitivity and specificity for diagnosing GDM, respectively. Conclusion: It is recommended to use FPG as a suitable screening test for GDM with acceptable specificity and sensitivity.
AB - Background: Many different tests have been introduced for screening gestational diabetes mellitus (GDM). The Objectives of this study were to determine both the diagnostic value of fasting plasma glucose (FPG) and the suitable cut-off point of plasma glucose with the best sensitivity and specificity for diagnosing gestational diabetes mellitus (GDM). Methods: This cross-sectional study was done on 242 women in Karaj-Iran who had at least one risk factor for GDM. Having conducted 50 gram glucose challenge test (GCT), the diagnostic values of FPG were determined by receiver operating characteristic curve (ROC). Then the level of plasma glucose, with the highest sensitivity and specificity rate, were determined for the diagnosis of GDM. Results: Based on the results of ROC curve, FPG with cut-off point ≥91 mg/dl revealed 63.89% and 76.56% sensitivity and specificity for diagnosing GDM, respectively. Conclusion: It is recommended to use FPG as a suitable screening test for GDM with acceptable specificity and sensitivity.
KW - FPG
KW - GDM
KW - Oral glucose tolerance test
KW - ROC curve
UR - http://www.scopus.com/inward/record.url?scp=81755166815&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:81755166815
SN - 1726-7544
VL - 10
SP - 1
EP - 5
JO - Iranian Journal of Diabetes and Lipid Disorders
JF - Iranian Journal of Diabetes and Lipid Disorders
ER -
