Exacerbations of COPD

William D-C Man, Arwel W. Jones

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Acute exacerbations requiring hospitalisation result in physical inactivity, exercise intolerance, and a deterioration in muscle function and health status that place COPD patients at high risk of readmission. High-quality clinical trial evidence shows improvements in exercise capacity and QoL with PR delivered immediately upon initiation, or within 3 weeks, of exacerbation treatment. Evidence for reductions in hospital readmissions and mortality is of lower quality, which may be due to the extensiveness or components of the programme. Few or no mild adverse events have been reported, but qualitative studies suggest that referral to an outpatient centre-based programme on the day of hospital discharge is not acceptable to many patients. Under-referral and barriers at a health service level have also limited implementation of PR during or following hospitalisation in routine clinical practice. Research to address these issues is underway, as it has the potential to make a significant impact on health services, given the known efficacy of peri- or post-exacerbation PR in clinical trials.
Original languageEnglish
Title of host publicationPulmonary Rehabilitation
EditorsAnne E. Holland, Simone Dal Corso, Martjin A. Spruit
Place of PublicationUnited Kingdom
PublisherEuropean Respiratory Society
Number of pages17
ISBN (Electronic)9781849841405
ISBN (Print)9781849841399
Publication statusPublished - Sep 2021

Publication series

NameERS Monograph
PublisherEuropean Respiratory Society
ISSN (Print)2312-508X
ISSN (Electronic)2312-5098

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