TY - JOUR
T1 - Evolutionary dynamics of carbapenem-resistant Acinetobacter baumannii circulating in Chilean hospitals
AU - Opazo-Capurro, Andrés
AU - San Martín, Iván
AU - Quezada-Aguiluz, Mario
AU - Morales-León, Felipe
AU - Domínguez-Yévenes, Mariana
AU - Lima, Celia A.
AU - Esposito, Fernanda
AU - Cerdeira, Louise
AU - Bello-Toledo, Helia
AU - Lincopan, Nilton
AU - González-Rocha, Gerardo
PY - 2019/9
Y1 - 2019/9
N2 - We analyze the evolutionary dynamics of ninety carbapenem-resistant Acinetobacter baumannii (CRAB)isolates collected between 1990 and 2015 in Chile. CRAB were identified at first in an isolate collected in 2005, which harbored the ISAba1-bla OXA-69 arrangement. Later, OXA-58- and OXA-23-producing A. baumannii strains emerged in 2007 and 2009, respectively. This phenomenon was associated with variations in the epidemiology of OXA-type carbapenemases, linked to nosocomial lineages belonging to ST109, ST162, ST15 (CC15)and ST318 (CC15).
AB - We analyze the evolutionary dynamics of ninety carbapenem-resistant Acinetobacter baumannii (CRAB)isolates collected between 1990 and 2015 in Chile. CRAB were identified at first in an isolate collected in 2005, which harbored the ISAba1-bla OXA-69 arrangement. Later, OXA-58- and OXA-23-producing A. baumannii strains emerged in 2007 and 2009, respectively. This phenomenon was associated with variations in the epidemiology of OXA-type carbapenemases, linked to nosocomial lineages belonging to ST109, ST162, ST15 (CC15)and ST318 (CC15).
KW - Acinetobacter baumannii
KW - Carbapenem-resistance
KW - CC15
KW - Chile
KW - OXA-type carbapenemases
KW - WHO's priority-pathogen
UR - http://www.scopus.com/inward/record.url?scp=85064828883&partnerID=8YFLogxK
U2 - 10.1016/j.meegid.2019.04.022
DO - 10.1016/j.meegid.2019.04.022
M3 - Article
C2 - 31029791
AN - SCOPUS:85064828883
SN - 1567-1348
VL - 73
SP - 93
EP - 97
JO - Infection, Genetics and Evolution
JF - Infection, Genetics and Evolution
ER -
