Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases

James Irving; Robert N Pike; Weiwen Dai; Dieter Bromme; Margaret D Worrall; Gary A Silverman; Theresa Ht Coetzer; Clive Dennison; S P Bottomley; James C Whisstock

Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases

James Irving, Robert N Pike, Weiwen Dai, Dieter Bromme, Margaret D Worrall, Gary A Silverman, Theresa Ht Coetzer, Clive Dennison, S P Bottomley, James C Whisstock

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

Original language	English
Pages (from-to)	4998 - 5004
Number of pages	7
Journal	Biochemistry
Volume	41
Issue number	15
Publication status	Published - 2002

Cite this

Irving, James ; Pike, Robert N ; Dai, Weiwen ; Bromme, Dieter ; Worrall, Margaret D ; Silverman, Gary A ; Coetzer, Theresa Ht ; Dennison, Clive ; Bottomley, S P ; Whisstock, James C. / Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases. In: Biochemistry. 2002 ; Vol. 41, No. 15. pp. 4998 - 5004.

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title = "Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases",

author = "James Irving and Pike, {Robert N} and Weiwen Dai and Dieter Bromme and Worrall, {Margaret D} and Silverman, {Gary A} and Coetzer, {Theresa Ht} and Clive Dennison and Bottomley, {S P} and Whisstock, {James C}",

year = "2002",

language = "English",

volume = "41",

pages = "4998 -- 5004",

journal = "Biochemistry",

issn = "0006-2960",

publisher = "American Chemical Society",

number = "15",

}

Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases. / Irving, James; Pike, Robert N; Dai, Weiwen; Bromme, Dieter; Worrall, Margaret D; Silverman, Gary A; Coetzer, Theresa Ht; Dennison, Clive; Bottomley, S P; Whisstock, James C.

In: Biochemistry, Vol. 41, No. 15, 2002, p. 4998 - 5004.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Evidence that serpin architecture intrinsically supports papain-like cystein protease inhibition: Engineering 1- abutrypsin to inhibit acathepsin proteases

AU - Irving, James

AU - Pike, Robert N

AU - Dai, Weiwen

AU - Bromme, Dieter

AU - Worrall, Margaret D

AU - Silverman, Gary A

AU - Coetzer, Theresa Ht

AU - Dennison, Clive

AU - Bottomley, S P

AU - Whisstock, James C

PY - 2002

Y1 - 2002

M3 - Article

VL - 41

SP - 4998

EP - 5004

JO - Biochemistry

JF - Biochemistry

SN - 0006-2960

IS - 15

ER -