TY - JOUR
T1 - EVestG Recordings are Vestibuloacoustic Signals
AU - Blakley, Brian
AU - Suleiman, Abdelbaset
AU - Rutherford, Grant
AU - Moussavi, Zahra
AU - Lithgow, Brian
N1 - Funding Information:
This study was supported by Neural Diagnostics
Publisher Copyright:
© 2018, Taiwanese Society of Biomedical Engineering.
PY - 2019/4/2
Y1 - 2019/4/2
N2 - A field potential can be defined as the ‘synchronous’ firing of many of vestibuloacoustic nerve fibres. Electrovestibulography has been considered as a method to record and detect vestibuloacoustic signals originating mainly from the vestibular system. A clear picture of the likely acoustic, vestibular or vestibuloacoustic origin and the physiologic basis of these field potentials is lacking. Recordings were conducted on anesthetized Guinea Pigs [ketamine (60 mg/kg) and xylazine (6 mg/kg)] to determine the origin of these minute spontaneous field potentials detected, recorded and averaged during Electrovestibulography recordings. Recordings were made with (1) normal hearing and balance (vestibular function), (2) following cisplatin deafening then (3) following both cisplatin deafening and gentamicin vestibular ablation. The detected minute spontaneous field potentials were determined to be both acoustic and vestibular in origin i.e., vestibuloacoustic. Based on the spontaneous activity of acoustic and vestibular nerve fibers arguments are presented that these field potentials are predominantly vestibular.
AB - A field potential can be defined as the ‘synchronous’ firing of many of vestibuloacoustic nerve fibres. Electrovestibulography has been considered as a method to record and detect vestibuloacoustic signals originating mainly from the vestibular system. A clear picture of the likely acoustic, vestibular or vestibuloacoustic origin and the physiologic basis of these field potentials is lacking. Recordings were conducted on anesthetized Guinea Pigs [ketamine (60 mg/kg) and xylazine (6 mg/kg)] to determine the origin of these minute spontaneous field potentials detected, recorded and averaged during Electrovestibulography recordings. Recordings were made with (1) normal hearing and balance (vestibular function), (2) following cisplatin deafening then (3) following both cisplatin deafening and gentamicin vestibular ablation. The detected minute spontaneous field potentials were determined to be both acoustic and vestibular in origin i.e., vestibuloacoustic. Based on the spontaneous activity of acoustic and vestibular nerve fibers arguments are presented that these field potentials are predominantly vestibular.
KW - Acoustic
KW - Electrovestibulography
KW - EVestG
KW - Vestibular
UR - http://www.scopus.com/inward/record.url?scp=85063282583&partnerID=8YFLogxK
U2 - 10.1007/s40846-018-0398-6
DO - 10.1007/s40846-018-0398-6
M3 - Article
AN - SCOPUS:85063282583
SN - 1609-0985
VL - 39
SP - 213
EP - 217
JO - Journal of Medical and Biological Engineering
JF - Journal of Medical and Biological Engineering
IS - 2
ER -