EVestG™: A diagnostic measure for schizophrenia

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6 Citations (Scopus)

Abstract

Schizophrenia is a severe mental illness associated with multiple neuropathological, neurochemical and genetic abnormalities. The benefits of a validated, quantitative diagnosis tool are well established. Electrovestibulography, a new method similar to ECOG, can detect and record neural activity generated by the vestibular system. The normal EVestG response as well as dynamic measures averaged "background-onAA" (onAA=acceleration phase of tilt) and "background-onBB" (onBB=deceleration phase of tilt) of excitatory (ipsi-lateral tilt) vestibular responses are compared for a small group of schizophrenia patients (n=4) and age matched healthy controls (n=10). Our preliminary results show an apparent discrimination between control and schizophrenia groups. Schizophrenia patients appear not only to exhibit an overall decreased EVestG signal amplitude but a suppressed dynamic response calculated by the averaged EVestG "background-onBB" measure. Increased sample size is required to validate these findings.

Original languageEnglish
Title of host publicationProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Pages4142-4145
Number of pages4
Publication statusPublished - 1 Dec 2008
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2008 - Vancouver Convention and Exhibition Centre, Vancouver, Canada
Duration: 20 Aug 200825 Aug 2008
Conference number: 30th

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2008
Abbreviated titleEMBS 2008
CountryCanada
CityVancouver
Period20/08/0825/08/08

Cite this

Haghgooie, S., Lithgow, B. J., Winograd-Gurvich, C., & Kulkarni, J. (2008). EVestG™: A diagnostic measure for schizophrenia. In Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 (pp. 4142-4145). [4650121]