Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis

Eleni Giannakis; Mary Macris; Linda Chan; Geoffrey W Tregear; Chrishan S. Samuel; John D. Wade

doi:10.1111/j.1749-6632.2009.03957.x

Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis

Eleni Giannakis, Mary Macris, Linda Chan, Geoffrey W Tregear, Chrishan S. Samuel, John D. Wade

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other › peer-review

Abstract

Surface-enhanced laser desorption ionization-time-of-flight mass spectrometry was employed to identify potential biomarkers for early-onset fibrosis. These biomarkers were then used to evaluate the efficacy of relaxin to reverse or ameliorate the development of the condition.

Original language	English
Title of host publication	Relaxin and Related Peptides Fifth International Conference
Pages	350-352
Number of pages	3
Volume	1160
DOIs	https://doi.org/10.1111/j.1749-6632.2009.03957.x
Publication status	Published - Apr 2009
Externally published	Yes

Publication series

Name	Annals of the New York Academy of Sciences
Volume	1160
ISSN (Print)	00778923
ISSN (Electronic)	17496632

Keywords

Fibrosis
Protein profiling
Relaxin knockout mice
SELDI-TOF mass spectrometry

Access to Document

10.1111/j.1749-6632.2009.03957.x

Link to publication in Scopus

Cite this

Giannakis, E., Macris, M., Chan, L., Tregear, G. W., Samuel, C. S., & Wade, J. D. (2009). Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis. In Relaxin and Related Peptides Fifth International Conference (Vol. 1160, pp. 350-352). (Annals of the New York Academy of Sciences; Vol. 1160). https://doi.org/10.1111/j.1749-6632.2009.03957.x

Giannakis, Eleni ; Macris, Mary ; Chan, Linda ; Tregear, Geoffrey W ; Samuel, Chrishan S. ; Wade, John D. / Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis. Relaxin and Related Peptides Fifth International Conference. Vol. 1160 2009. pp. 350-352 (Annals of the New York Academy of Sciences).

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title = "Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis",

abstract = "Surface-enhanced laser desorption ionization-time-of-flight mass spectrometry was employed to identify potential biomarkers for early-onset fibrosis. These biomarkers were then used to evaluate the efficacy of relaxin to reverse or ameliorate the development of the condition.",

keywords = "Fibrosis, Protein profiling, Relaxin knockout mice, SELDI-TOF mass spectrometry",

author = "Eleni Giannakis and Mary Macris and Linda Chan and Tregear, {Geoffrey W} and Samuel, {Chrishan S.} and Wade, {John D.}",

year = "2009",

month = apr,

doi = "10.1111/j.1749-6632.2009.03957.x",

language = "English",

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Giannakis, E, Macris, M, Chan, L, Tregear, GW, Samuel, CS & Wade, JD 2009, Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis. in Relaxin and Related Peptides Fifth International Conference. vol. 1160, Annals of the New York Academy of Sciences, vol. 1160, pp. 350-352. https://doi.org/10.1111/j.1749-6632.2009.03957.x

Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis. / Giannakis, Eleni; Macris, Mary; Chan, Linda; Tregear, Geoffrey W; Samuel, Chrishan S.; Wade, John D.

Relaxin and Related Peptides Fifth International Conference. Vol. 1160 2009. p. 350-352 (Annals of the New York Academy of Sciences; Vol. 1160).

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other › peer-review

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Giannakis E, Macris M, Chan L, Tregear GW, Samuel CS, Wade JD. Evaluation of relaxin's antifibrotic action by SELDI-TOF mass spectrometry-based profiling of relaxin knockout mice, a model of progressive fibrosis. In Relaxin and Related Peptides Fifth International Conference. Vol. 1160. 2009. p. 350-352. (Annals of the New York Academy of Sciences). https://doi.org/10.1111/j.1749-6632.2009.03957.x