Evaluation of hepatoprotective effect of polyherbal formulation - Livomyn

Rakesh Kenjale, Mohd Farooq Shaikh, Sadhana Sathaye

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The liver is the most important organ and has great capacity to detoxify and synthesize useful substances. Therefore liver diseases like hepatic fibrosis, liver cirrhosis, hepatitis and hepatocellular carcinoma are of global concern. In absence of reliable hepatoprotective agent in modern medicine the herbal formulations are the most preferred therapy for liver injury. The present study investigates the efficacy of one such polyherbal formulation - Livomyn as a hepatoprotective formula against ethanol, CCl4 and galactosamine induced hepatotoxicity in Wistar rats. The evaluation of blood serum parameters exhibits significant reduction in the levels of albumin, bilirubin, SGOT, SGPT, LPO, alkaline phosphate and cholesterol whereas significant increase in Total protein and reduced GSH levels in Livomyn treated groups. The hepatoprotective effect is attributed to synergistic effect of potent antioxidant and hepatoprotective property of various medicinal plant extracts in Livomyn formulation.

Original languageEnglish
Pages (from-to)338-343
Number of pages6
JournalInternational Journal of Research in Pharmaceutical Sciences
Volume2
Issue number3
Publication statusPublished - 8 Jul 2011
Externally publishedYes

Keywords

  • Antioxidant
  • Hepatoprotective
  • Livomyn
  • Polyherbal formulation

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