Evaluation of differences in patient and physician perception of benefit and risks of aspirin and antifibrinolytic therapy in cardiac surgery

Paul S Myles, Georgina E Thompson, Christine Fedorow, Catherine Farrington, Nicole Sheridan

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3 Citations (Scopus)


It is unclear whether physicians and patients have similar concerns and preferences when considering benefit and risks of aspirin and antifibrinolytic therapy for cardiac surgery. We surveyed both groups to ascertain their perceptions and preferences for treatment in this setting. Both preoperative and postoperative cardiac surgical patients and the physician craft groups caring for them (cardiology, surgery, anaesthesia/critical care), were provided with estimates of benefits and risks of aspirin and antifibrinolytic therapy. All study partici- pants were asked to stipulate the minimal absolute risk reduction required for them to agree to such therapy. When compared with the cardiac surgical patients they treat, physicians required a smaller thrombotic risk reduction with aspirin whilst accepting its known increased risk of bleeding. This was significantly different in a high-risk stroke setting (incidence 5 ) where the required relative risk reduction with aspirin use for physicians was 20 versus patients 40 (P
Original languageEnglish
Pages (from-to)592 - 598
Number of pages7
JournalAnaesthesia and Intensive Care
Issue number5
Publication statusPublished - 2014

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