Evaluating the impact of air pollution on the incidence of out-of-hospital cardiac arrest in the Perth Metropolitan Region: 2000-2010

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Abstract

Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue. Several studies have found that an increased level of ambient particulate matter (PM) smaller than 2.5 microns (PM2.5) is associated with an increased risk of OHCA. We investigated the relationship between air pollution levels and the incidence of OHCA in Perth, Western Australia. Methods: We linked St John Ambulance OHCA data of presumed cardiac aetiology with Perth air pollution data from seven monitors which recorded hourly levels of PM smaller than 2.5 and 10 microns (PM2.5/PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3). We used a case-crossover design to estimate the strength of association between ambient air pollution levels and risk of OHCA. Results: Between 2000 and 2010, there were 8551 OHCAs that met the inclusion criteria. Of these, 5624 (65.8 ) occurred in men. An IQR increase in the 24 and 48 h averages of PM2.5 was associated with 10.6 (OR 1.106, 95 CI 1.038 to 1.180) and 13.6 (OR 1.136, 95 CI 1.051 to 1.228) increases, respectively, in the risk of OHCA. CO showed a consistent association with increased risk of an OHCA. An IQR increase in the 4 h average concentration of CO was associated with a 2.2 (OR 1.022, 95 CI 1.002 to 1.042) increase in risk of an OHCA. When we restricted our analysis of CO to arrests occurring between 6:00 and 10:00, we found a 4.4 (95 CI 1.1 to 7.8 ) increase in risk of an OHCA. Conclusions: Elevated ambient PM2.5 and CO are associated with an increased risk of OHCA.
Original languageEnglish
Pages (from-to)6 - 12
Number of pages7
JournalJournal of Epidemiology and Community Health
Volume68
Issue number1
DOIs
Publication statusPublished - 2014

Cite this

@article{cb6a39d3af4e4e8c9294c69d63dd0b73,
title = "Evaluating the impact of air pollution on the incidence of out-of-hospital cardiac arrest in the Perth Metropolitan Region: 2000-2010",
abstract = "Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue. Several studies have found that an increased level of ambient particulate matter (PM) smaller than 2.5 microns (PM2.5) is associated with an increased risk of OHCA. We investigated the relationship between air pollution levels and the incidence of OHCA in Perth, Western Australia. Methods: We linked St John Ambulance OHCA data of presumed cardiac aetiology with Perth air pollution data from seven monitors which recorded hourly levels of PM smaller than 2.5 and 10 microns (PM2.5/PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3). We used a case-crossover design to estimate the strength of association between ambient air pollution levels and risk of OHCA. Results: Between 2000 and 2010, there were 8551 OHCAs that met the inclusion criteria. Of these, 5624 (65.8 ) occurred in men. An IQR increase in the 24 and 48 h averages of PM2.5 was associated with 10.6 (OR 1.106, 95 CI 1.038 to 1.180) and 13.6 (OR 1.136, 95 CI 1.051 to 1.228) increases, respectively, in the risk of OHCA. CO showed a consistent association with increased risk of an OHCA. An IQR increase in the 4 h average concentration of CO was associated with a 2.2 (OR 1.022, 95 CI 1.002 to 1.042) increase in risk of an OHCA. When we restricted our analysis of CO to arrests occurring between 6:00 and 10:00, we found a 4.4 (95 CI 1.1 to 7.8 ) increase in risk of an OHCA. Conclusions: Elevated ambient PM2.5 and CO are associated with an increased risk of OHCA.",
author = "Straney, {Lahn David John} and Finn, {Judith C} and Dennekamp, {Martine Neeltje} and Alexandra Bremner and Tonkin, {Andrew Maxwell} and Jacobs, {Ian G}",
year = "2014",
doi = "10.1136/jech-2013-202955",
language = "English",
volume = "68",
pages = "6 -- 12",
journal = "Journal of Epidemiology and Community Health",
issn = "0143-005X",
publisher = "BMJ Publishing Group",
number = "1",

}

TY - JOUR

T1 - Evaluating the impact of air pollution on the incidence of out-of-hospital cardiac arrest in the Perth Metropolitan Region: 2000-2010

AU - Straney, Lahn David John

AU - Finn, Judith C

AU - Dennekamp, Martine Neeltje

AU - Bremner, Alexandra

AU - Tonkin, Andrew Maxwell

AU - Jacobs, Ian G

PY - 2014

Y1 - 2014

N2 - Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue. Several studies have found that an increased level of ambient particulate matter (PM) smaller than 2.5 microns (PM2.5) is associated with an increased risk of OHCA. We investigated the relationship between air pollution levels and the incidence of OHCA in Perth, Western Australia. Methods: We linked St John Ambulance OHCA data of presumed cardiac aetiology with Perth air pollution data from seven monitors which recorded hourly levels of PM smaller than 2.5 and 10 microns (PM2.5/PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3). We used a case-crossover design to estimate the strength of association between ambient air pollution levels and risk of OHCA. Results: Between 2000 and 2010, there were 8551 OHCAs that met the inclusion criteria. Of these, 5624 (65.8 ) occurred in men. An IQR increase in the 24 and 48 h averages of PM2.5 was associated with 10.6 (OR 1.106, 95 CI 1.038 to 1.180) and 13.6 (OR 1.136, 95 CI 1.051 to 1.228) increases, respectively, in the risk of OHCA. CO showed a consistent association with increased risk of an OHCA. An IQR increase in the 4 h average concentration of CO was associated with a 2.2 (OR 1.022, 95 CI 1.002 to 1.042) increase in risk of an OHCA. When we restricted our analysis of CO to arrests occurring between 6:00 and 10:00, we found a 4.4 (95 CI 1.1 to 7.8 ) increase in risk of an OHCA. Conclusions: Elevated ambient PM2.5 and CO are associated with an increased risk of OHCA.

AB - Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue. Several studies have found that an increased level of ambient particulate matter (PM) smaller than 2.5 microns (PM2.5) is associated with an increased risk of OHCA. We investigated the relationship between air pollution levels and the incidence of OHCA in Perth, Western Australia. Methods: We linked St John Ambulance OHCA data of presumed cardiac aetiology with Perth air pollution data from seven monitors which recorded hourly levels of PM smaller than 2.5 and 10 microns (PM2.5/PM10), carbon monoxide (CO), sulfur dioxide (SO2), nitrogen dioxide (NO2) and ozone (O3). We used a case-crossover design to estimate the strength of association between ambient air pollution levels and risk of OHCA. Results: Between 2000 and 2010, there were 8551 OHCAs that met the inclusion criteria. Of these, 5624 (65.8 ) occurred in men. An IQR increase in the 24 and 48 h averages of PM2.5 was associated with 10.6 (OR 1.106, 95 CI 1.038 to 1.180) and 13.6 (OR 1.136, 95 CI 1.051 to 1.228) increases, respectively, in the risk of OHCA. CO showed a consistent association with increased risk of an OHCA. An IQR increase in the 4 h average concentration of CO was associated with a 2.2 (OR 1.022, 95 CI 1.002 to 1.042) increase in risk of an OHCA. When we restricted our analysis of CO to arrests occurring between 6:00 and 10:00, we found a 4.4 (95 CI 1.1 to 7.8 ) increase in risk of an OHCA. Conclusions: Elevated ambient PM2.5 and CO are associated with an increased risk of OHCA.

UR - http://jech.bmj.com/content/68/1/6.full.pdf+html

U2 - 10.1136/jech-2013-202955

DO - 10.1136/jech-2013-202955

M3 - Article

VL - 68

SP - 6

EP - 12

JO - Journal of Epidemiology and Community Health

JF - Journal of Epidemiology and Community Health

SN - 0143-005X

IS - 1

ER -