Evaluación hematológica diaria durante una ultramaratón de múltiples etapas de 230 km

Translated title of the contribution: Daily hematologic assessment during a 230-km multistage ultramarathon

Luciele Guerra Minuzzi, Ana Maria Teixeira, Humberto Moreira Carvalho, Ricardo José da Costa, Luis Rama

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)


Introduction: The popularity of ultra-endurance events is increasing worldwide. However, information about hematological parameters during repeated bouts of long-duration running, such as stages during a multi-stage ultramarathon (MSUM) is scarce. Objective: The purpose of the study was to monitor daily hematologic assessment in a 230-km multistage ultramarathon (MSUM) in hot environmental conditions. Methods: Eleven male and three female (n = 14) ultra-endurance runners entered this MSUM, which was conducted over five stages, covering a total distance of 230 km in hot ambient conditions. Peripheral blood samples were collected before and after each stage to determine leukocyte and erythrocytes parameters. Results: Multilevel modelling considering all measurement points showed an increase for whole blood leukocyte and granulocyte counts at five stages of the MSUM and for monocytes until Stage 3 of the race. For erythrocyte parameters, decreases across stages were observed in hemoglobin concentration and hematocrit responses when computing/considering all measurement points. Conclusions: The results indicate that MSUM in a hot environment leads to a greater impact on leukocyte population responses and platelet variation in the initial stages of the race. We suggest that athletes may have a decrease in immune function in the early stages of the MSUM, probably with some transient risk of infectious. Nevertheless, a physiological adaptation to physical exertion and heat mitigates these changes in the subsequent stages of MSUM. Level of Evidence III; Case-control study.

Translated title of the contributionDaily hematologic assessment during a 230-km multistage ultramarathon
Original languageSpanish
Pages (from-to)206-211
Number of pages6
JournalRevista Brasileira de Medicina do Esporte
Issue number3
Publication statusPublished - 1 May 2018


  • Athletes
  • Erythrocytes
  • Infection
  • Leukocytes
  • Running

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