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Etiology and treatment challenges for neurotraumatic and psychiatric disorders

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Abstract

Neurotraumatic and psychiatric disorders pose significant challenges in terms of etiology and treatment. These disorders encompass a diverse range of conditions resulting from traumatic brain injuries (TBIs) and various psychiatric conditions. Understanding the etiological factors contributing to the development of these disorders is crucial for effective management and targeted interventions. Additionally, the complex interplay between neurological and psychiatric aspects further complicates diagnosis and treatment strategies. This book chapter explores the etiological factors associated with neurotraumatic and psychiatric disorders, including genetic, environmental, and psychological contributors. It highlights the role of neuroinflammation, neurotransmitter imbalances, and neuroplasticity alterations in the pathophysiology of these conditions. Furthermore, this chapter addresses the challenges encountered in the treatment of these disorders, such as the limited efficacy of current therapies, high comorbidity rates, and individual variations in treatment response. Novel therapeutic approaches, including pharmacological interventions, psychotherapy, and emerging neuromodulation techniques, are discussed in the context of their potential to improve patient outcomes. The application of precision medicine approaches is also explored. Ultimately, a comprehensive understanding of the etiology and treatment challenges of neurotraumatic and psychiatric disorders is crucial for advancing patient care and developing innovative strategies to improve the lives of affected individuals.

Original languageEnglish
Title of host publicationNovel Drug Delivery Systems in the Management of CNS Disorders
EditorsPooja A. Chawla, Raimar Loebenberg, Kamal Dua, Vinay Parikh, Viney Chawla
Place of PublicationLondon UK
PublisherElsevier
Chapter26
Pages343-352
Number of pages10
Edition1st
ISBN (Print)9780443134746
DOIs
Publication statusPublished - 2024

Keywords

  • Anxiety
  • Depression
  • Neuropathology
  • Precision medicine
  • Traumatic brain injury

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