Ethyl 2-(4-hydroxy-3-methoxyphenyl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H- benzimidazole-5-carboxylate monohydrate

In the title compound, C ₂₄H ₂₇N ₃O ₅·H ₂O, the essentially planar benzimidazole ring system [maximum deviation = 0.020(1) Å] forms dihedral angles of 54.10(11) and 67.79(6)°, respectively, with the mean plane of pyrrolidin-2-one ring and the benzene ring. The pyrrolidin-2-one ring adopts an envelope conformation with one of the methylene C atoms at the flap. An intramolecular C-H··· π interaction is observed. In the crystal, O-H··· O and O-H··· N hydrogen bonds link the two components into a double-tape structure along the a axis. The crystal packing is further stabilized by weak π-π stacking [centroid-centroid distance = 3.6632(9) Å] and C-H··· O interactions.