Ethyl 2-(4-hydroxy-3-methoxyphenyl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H- benzimidazole-5-carboxylate monohydrate

Yeong Keng Yoon, Mohamed Ashraf Ali, Tan Soo Choon, Safra Izuani Jama Asik, Ibrahim Abdul Razak

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

In the title compound, C 24H 27N 3O 5·H 2O, the essentially planar benzimidazole ring system [maximum deviation = 0.020(1) Å] forms dihedral angles of 54.10(11) and 67.79(6)°, respectively, with the mean plane of pyrrolidin-2-one ring and the benzene ring. The pyrrolidin-2-one ring adopts an envelope conformation with one of the methylene C atoms at the flap. An intramolecular C-H··· π interaction is observed. In the crystal, O-H··· O and O-H··· N hydrogen bonds link the two components into a double-tape structure along the a axis. The crystal packing is further stabilized by weak π-π stacking [centroid-centroid distance = 3.6632(9) Å] and C-H··· O interactions.

Original languageEnglish
Pages (from-to)o87-o88
Number of pages2
JournalActa Crystallographica Section E: Structure Reports Online
Volume68
Issue number1
DOIs
Publication statusPublished - Jan 2012
Externally publishedYes

Keywords

  • Data-to-parameter ratio = 21.4
  • Mean σ(C-C) = 0.003 Å
  • R factor = 0.055
  • Single-crystal X-ray study
  • T = 296 K
  • wR factor = 0.185

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