Ethambutol

Tony M. Korman

Ethambutol

Research output: Chapter in Book/Report/Conference proceeding › Chapter (Book) › Other › peer-review

Abstract

Ethambutol was discovered at Lederle Laboratories in 1961, when randomly selected synthetic compounds were being tested for antituberculosis activity. Chemically, it is dextro-2, 2'-(ethylenediimino)-di-1-butanol dihydrochloride, and it has a high degree of activity against Mycobacterium tuberculosis (Thomas et al., 1961). The chemical formula of ethambutol dihydrochloride is C₁0H₂₄N₂O₂. 2(HCl) and its molecular weight is 277.23; its molecular structure is shown in Figure 124.1. Ethambutol is a useful drug for the treatment of tuberculosis and infections due to Mycobacterium avium complex and other nontuberculous mycobacteria.

Original language	English
Title of host publication	Kucers the Use of Antibiotics
Subtitle of host publication	A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs
Editors	M. Lindsay Grayson
Place of Publication	Boca Raton FL USA
Publisher	CRC Press
Chapter	124
Pages	2346-2360
Number of pages	15
Edition	7th
ISBN (Electronic)	9781498747967
ISBN (Print)	9781498747950
Publication status	Published - 2 Oct 2017

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Ethambutol",

abstract = "Ethambutol was discovered at Lederle Laboratories in 1961, when randomly selected synthetic compounds were being tested for antituberculosis activity. Chemically, it is dextro-2, 2'-(ethylenediimino)-di-1-butanol dihydrochloride, and it has a high degree of activity against Mycobacterium tuberculosis (Thomas et al., 1961). The chemical formula of ethambutol dihydrochloride is C10H24N2O2. 2(HCl) and its molecular weight is 277.23; its molecular structure is shown in Figure 124.1. Ethambutol is a useful drug for the treatment of tuberculosis and infections due to Mycobacterium avium complex and other nontuberculous mycobacteria.",

author = "Korman, {Tony M.}",

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editor = "Grayson, {M. Lindsay }",

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publisher = "CRC Press",

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T1 - Ethambutol

AU - Korman, Tony M.

PY - 2017/10/2

Y1 - 2017/10/2

N2 - Ethambutol was discovered at Lederle Laboratories in 1961, when randomly selected synthetic compounds were being tested for antituberculosis activity. Chemically, it is dextro-2, 2'-(ethylenediimino)-di-1-butanol dihydrochloride, and it has a high degree of activity against Mycobacterium tuberculosis (Thomas et al., 1961). The chemical formula of ethambutol dihydrochloride is C10H24N2O2. 2(HCl) and its molecular weight is 277.23; its molecular structure is shown in Figure 124.1. Ethambutol is a useful drug for the treatment of tuberculosis and infections due to Mycobacterium avium complex and other nontuberculous mycobacteria.

AB - Ethambutol was discovered at Lederle Laboratories in 1961, when randomly selected synthetic compounds were being tested for antituberculosis activity. Chemically, it is dextro-2, 2'-(ethylenediimino)-di-1-butanol dihydrochloride, and it has a high degree of activity against Mycobacterium tuberculosis (Thomas et al., 1961). The chemical formula of ethambutol dihydrochloride is C10H24N2O2. 2(HCl) and its molecular weight is 277.23; its molecular structure is shown in Figure 124.1. Ethambutol is a useful drug for the treatment of tuberculosis and infections due to Mycobacterium avium complex and other nontuberculous mycobacteria.

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M3 - Chapter (Book)

AN - SCOPUS:85056691671

SN - 9781498747950

SP - 2346

EP - 2360

BT - Kucers the Use of Antibiotics

A2 - Grayson, M. Lindsay

PB - CRC Press

CY - Boca Raton FL USA

ER -

Ethambutol

Abstract

UN SDGs

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Ethambutol

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